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TBC1D2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9209639

TBC1D2 acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivativation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion. More details

$240 / 0.08 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBC1D2, Polyclonal Antibody
Full Product Name
TBC1D2 Antibody (Center)
Product Gene Name
Product Synonym Names
TBC1 domain family member 2A; Armus; Prostate antigen recognized and identified by SEREX 1; PARIS-1; TBC1D2; PARIS1; PP8997; TBC1D2A
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.5 (lot specific)
Specificity
This TBC1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the Central region of human TBC1D2.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
TBC1D2 peptide (MBS9223597) is used for blocking the activity of TBC1D2 antibody (MBS9209639)
Molecular Weight
105414
Immunogen Sequence Positions
438-465
OMIM
609871
3D Structure
ModBase 3D Structure for Q9BYX2
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN

Product Categories/Family for anti-TBC1D2 antibody

Applications Tested/Suitable for anti-TBC1D2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TBC1D2 antibody
WB~~1:1000

Western Blot (WB) of anti-TBC1D2 antibody

TBC1D2 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TBC1D2 antibody detected the TBC1D2 protein (arrow).
Rabbit Anti-TBC1D2 Polyclonal Antibody – Cat# MBS9209639

Product References and Citations for anti-TBC1D2 antibody

Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Zhou, Y., et al. Biochem. Biophys. Res. Commun. 290(2):830-838(2002)

Other Notes

Small volumes of anti-TBC1D2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBC1D2 purchase

MBS9209639 is an antibody targeting TBC1D2. Also known as TBC1D2 Antibody (Center). Reactive in Human, mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1D2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TBC1 domain family member 2A isoform 1
NCBI Official Synonym Full Names
TBC1 domain family, member 2
NCBI Official Symbol
TBC1D2
NCBI Official Synonym Symbols
PARIS1; PARIS-1; TBC1D2A
UniProt Protein Name
TBC1 domain family member 2A
UniProt Synonym Protein Names
Armus; Prostate antigen recognized and identified by SEREX 1; PARIS-1
Protein Family
UniProt Gene Name
TBC1D2
UniProt Synonym Gene Names
PARIS1; PP8997; TBC1D2A; PARIS-1
UniProt Entry Name
TBD2A_HUMAN
NCBI Protein Information
TBC1 domain family member 2A

UniProt Comments for TBC1D2

TBC1D2: a putative GTPase activating protein for Rab family protein(s). Expressed in a broad range of tissues. Differentially expressed in prostate normal and cancer cells.

Protein type: GAPs, Rab; GAPs

Chromosomal Location of Human Ortholog: 9q22.33

Cellular Component: cytoplasmic membrane-bound vesicle; cytoplasmic vesicle; cell junction

Molecular Function: protein binding; cadherin binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TBC1D2 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with TBC1D2 and Lung
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