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TOB1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6502782

MBS6502782 is an antibody targeting TOB1. Also known as TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB) (MaxLight 750). Reactive in Human, Mouse. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TOB1, Polyclonal Antibody
Full Product Name
TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB) (MaxLight 750)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human TOB1. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
38,155 Da
OMIM
605523
3D Structure
ModBase 3D Structure for P50616
Immunogen
Synthetic peptide selected from the N-terminal region of human TOB1 (KLH).
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-TOB1 antibody

Applications Tested/Suitable for anti-TOB1 antibody
Western Blot (WB), FLISA
Application Notes for anti-TOB1 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-TOB1 antibody

1. Suzuki, T., et.al., Genes Dev. 16(11), 1356-1370 (2002). 2. Yoshida, Y., et.al., Cell 103(7), 1085-1097 (2000).

Other Notes

Small volumes of anti-TOB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TOB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein Tob1 isoform 1
NCBI Official Synonym Full Names
transducer of ERBB2, 1
NCBI Official Symbol
TOB1
NCBI Official Synonym Symbols
TOB; TROB; APRO6; PIG49; TROB1
UniProt Protein Name
Protein Tob1
UniProt Synonym Protein Names
Transducer of erbB-2 1
Protein Family
UniProt Gene Name
TOB1
UniProt Synonym Gene Names
TOB; TROB1
UniProt Entry Name
TOB1_HUMAN
NCBI Protein Information
protein Tob1

NCBI Summary for TOB1

This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
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UniProt Comments for TOB1

TOB1: Anti-proliferative protein that interacts with the erbB- 2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. Belongs to the BTG family.

Protein type: Adaptor/scaffold; Cell cycle regulation

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytoplasm; nucleus; CCR4-NOT complex

Molecular Function: protein binding; SH3/SH2 adaptor activity; SMAD binding; receptor tyrosine kinase binding; transcription corepressor activity

Biological Process: negative regulation of cell proliferation; positive regulation of signal transduction; negative regulation of translation; negative regulation of osteoblast differentiation; SMAD protein nuclear translocation; negative regulation of BMP signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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