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TRIOBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129278
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This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRIOBP, Polyclonal Antibody
Full Product Name
TRIOBP Polyclonal Antibody
Product Gene Name
anti-TRIOBP antibody
Product Synonym Names
TARA; DFNB28; dJ37E16.4; HRIHFB2122
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
2365
OMIM
gene 609823
3D Structure
ModBase 3D Structure for Q9H2D6
Species
Human
Immunogen
Recombinant protein of human TRIOBP
Calculated Molecular Weight
261kDa

Product Categories/Family for anti-TRIOBP antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRIOBP antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-TRIOBP antibody
WB: 1:500-1:2000
IF: 1:50-1:100

Western Blot (WB) of anti-TRIOBP antibody

Western blot analysis of extracts of various cell lines, using TRIOBP antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 15s.
Rabbit Anti-TRIOBP Polyclonal Antibody – Cat# MBS129278

Other Notes

Small volumes of anti-TRIOBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIOBP purchase

MBS129278 is an antibody targeting TRIOBP. Also known as TRIOBP Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIOBP. It may not necessarily be applicable to this product.

NCBI GI #
90110075
NCBI GeneID
11078
NCBI Accession #
Q9H2D6.3
UniProt Primary Accession #
Q9H2D6
UniProt Secondary Accession #
O94797; Q2PZW8; Q2Q3Z9; Q2Q400; Q5R3M6; Q96DW1; Q9BT77; B1AHD4; B1AHD7; F2Z2W0; F8W6V6
UniProt Related Accession #
Q9H2D6
NCBI Official Full Name
TRIO and F-actin-binding protein
NCBI Official Synonym Full Names
TRIO and F-actin binding protein
NCBI Official Symbol
TRIOBP
NCBI Official Synonym Symbols
TARA; TAP68; DFNB28; dJ37E16.4; HRIHFB2122
UniProt Protein Name
TRIO and F-actin-binding protein
UniProt Synonym Protein Names
Protein Tara; Trio-associated repeat on actin
Protein Family
TRIO and F-actin-binding protein
UniProt Gene Name
TRIOBP
UniProt Synonym Gene Names
KIAA1662; TARA
UniProt Entry Name
TARA_HUMAN
NCBI Protein Information
TRIO and F-actin-binding protein; protein Tara; tara-like protein; trio-associated repeat on actin

UniProt Comments for TRIOBP

Tara: May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover. Defects in TRIOBP are the cause of deafness autosomal recessive type 28 (DFNB28). 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Actin-binding; Cytoskeletal

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: focal adhesion; cytoplasm; microtubule organizing center; midbody; nucleus; actin cytoskeleton

Molecular Function: actin filament binding; ubiquitin protein ligase binding; GTP-Rho binding; myosin II binding

Biological Process: mitosis; actin modification; cell division; barbed-end actin filament capping

Disease: Deafness, Autosomal Recessive 28
Show more

Research Articles on TRIOBP

1. TAP68 functions in mediating TRF1-tankyrase 1 localization to the centrosome and in mitotic regulation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TRIOBP antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with TRIOBP and Nervous System Diseases
 Ovarian Neoplasms Antibodies  >1 publications with TRIOBP and Ovarian Neoplasms
 Breast Neoplasms Antibodies  >1 publications with TRIOBP and Breast Neoplasms
 Lung Neoplasms Antibodies  >1 publications with TRIOBP and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with TRIOBP and Neoplasms, Experimental
 Necrosis Antibodies  >1 publications with TRIOBP and Necrosis

Organs/Tissues associated with anti-TRIOBP antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with TRIOBP and Blood
 Kidney Antibodies  >2 publications with TRIOBP and Kidney
 Brain Antibodies  >2 publications with TRIOBP and Brain
 Lymph Antibodies  >1 publications with TRIOBP and Lymph
 Muscle Antibodies  >1 publications with TRIOBP and Muscle
 Lymph Node Antibodies  >1 publications with TRIOBP and Lymph Node
 Testis Antibodies  >1 publications with TRIOBP and Testis
 Embryonic Tissue Antibodies  >1 publications with TRIOBP and Embryonic Tissue
 Eye Antibodies  >1 publications with TRIOBP and Eye
 Bone Marrow Antibodies  >1 publications with TRIOBP and Bone Marrow
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