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TSTA3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2563049

Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TSTA3, Polyclonal Antibody
Full Product Name
TSTA3 Polyclonal Antibody
Product Gene Name
anti-TSTA3 antibody
Product Synonym Names
3 5 epimerase/4 reductase; 5-epimerase-4-reductase; Anti TSTA3; EC 1.1.1.271; FCL; FX; GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase; GDP 4 keto 6 deoxy D mannose epimerase reductase; GDP L fucose synthase; GDP-4-keto-6-deoxy-D-mannose-3; GDP-L-fucose synthase; P35B; Protein FX; Red cell NADP(H) binding protein; Red cell NADP(H)-binding protein; SDR4E1; Short chain dehydrogenase/reductase family 4E member 1; Short-chain dehydrogenase/reductase family 4E member 1; Tissue specific transplantation antigen 3; Tissue specific transplantation antigen P35B; TSTA3; TSTA3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
1.44mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
137020
3D Structure
ModBase 3D Structure for Q13630
Immunogen
Fusion protein of human TSTA3
Conjugation
Unconjugated

Product Categories/Family for anti-TSTA3 antibody

Metabolism; Signal Transduction
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TSTA3 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-TSTA3 antibody
IHC: 1:50-1:200
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-TSTA3 antibody

Immunohistochemistry of paraffin-embedded Human brain tissue using TSTA3 Polyclonal Antibody at dilution of 1:80(×200)
Rabbit Anti-TSTA3 Polyclonal Antibody – Cat# MBS2563049

Immunohistochemistry (IHC) of anti-TSTA3 antibody

Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TSTA3 Polyclonal Antibody at dilution of 1:80(×200)
Rabbit Anti-TSTA3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2563049

Other Notes

Small volumes of anti-TSTA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TSTA3 purchase

MBS2563049 is an antibody targeting TSTA3. Also known as TSTA3 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TSTA3. It may not necessarily be applicable to this product.

NCBI GI #
4507709
NCBI GeneID
7264
NCBI Accession #
NP_003304.1
NCBI Related Accession #
BC001941
UniProt Primary Accession #
Q13630
UniProt Related Accession #
Q13630
GenBank Nucleotide #
NP_003304.1
NCBI Official Full Name
GDP-L-fucose synthase isoform 2
NCBI Official Synonym Full Names
tissue specific transplantation antigen P35B
NCBI Official Symbol
TSTA3
NCBI Official Synonym Symbols
FX; P35B; SDR4E1
UniProt Protein Name
GDP-L-fucose synthase
UniProt Synonym Protein Names
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; Protein FX; Red cell NADP(H)-binding protein; Short-chain dehydrogenase/reductase family 4E member 1
UniProt Gene Name
TSTA3
UniProt Synonym Gene Names
SDR4E1
UniProt Entry Name
FCL_HUMAN
NCBI Protein Information
GDP-L-fucose synthase

UniProt Comments for TSTA3

TSTA3: Two step NADP-dependent conversion of GDP-4-dehydro-6- deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the fucose synthase family.

Protein type: Oxidoreductase; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 1.1.1.271

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: cytoplasm

Molecular Function: GDP-L-fucose synthase activity; electron carrier activity; isomerase activity; coenzyme binding; GDP-4-dehydro-D-rhamnose reductase activity

Biological Process: leukocyte adhesion; cytolysis; GDP-mannose metabolic process; 'de novo' GDP-L-fucose biosynthetic process
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Research Articles on TSTA3

1. tissue-specific transplantation antigen P35B may serve as a novel biomarker for prognosis of patients with esophageal squamous cell carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TSTA3 antibody

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 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
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 GDP-L-fucose Biosynthesis I (from GDP-D-mannose) Pathway antibodies  GDP-L-fucose Biosynthesis I (from GDP-D-mannose) Pathway Diagram
 GDP-fucose Biosynthesis Pathway antibodies  GDP-fucose Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
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