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XLF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8292167

MBS8292167 is an antibody targeting XLF. Reactive in Human, Mouse. Host: Rabbit. Rabbit polyclonal antibody to XLF More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
XLF, Polyclonal Antibody
Full Product Name
Anti-XLF Antibody
Product Gene Name
Product Synonym Gene Name
NHEJ1
Product Synonym Names
XLF; Non-homologous end-joining factor 1; Protein cernunnos; XRCC4-like factor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
Purified by immunogen affinity chromatography
Specificity
Recognizes endogenous levels of XLF protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
35,291 Da
OMIM
AJ972687 mRNA
3D Structure
ModBase 3D Structure for Q9H9Q4
Immunogen
Recombinant full length protein of human XLF
Applications Tested/Suitable for anti-XLF antibody
Western Blot (WB)
Application Notes for anti-XLF antibody
WB: 1/500 - 1/2000

Western Blot (WB) of anti-XLF antibody

Western blot analysis of XLF expression in Hela (A), Jurkat (B) whole cell lysates.
Rabbit Anti-XLF Polyclonal Antibody – Cat# MBS8292167

Other Notes

Small volumes of anti-XLF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for XLF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
non-homologous end-joining factor 1
NCBI Official Synonym Full Names
non-homologous end joining factor 1
NCBI Official Symbol
NHEJ1
NCBI Official Synonym Symbols
XLF
UniProt Protein Name
Non-homologous end-joining factor 1
UniProt Synonym Protein Names
Protein cernunnos; XRCC4-like factor
Protein Family
UniProt Gene Name
NHEJ1
UniProt Synonym Gene Names
XLF
NCBI Protein Information
non-homologous end-joining factor 1

NCBI Summary for XLF

Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]
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UniProt Comments for XLF

DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17470781). Binds DNA in a length-dependent manner (PubMed:17317666).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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