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ACO1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2518750

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ACO1, Polyclonal Antibody
Full Product Name
ACO1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
IRP1; ACONS; IREB1; IREBP; IREBP1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.5mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
85,368 Da
Immunogen
Synthetic peptide of human ACO1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ACO1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ACO1 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-ACO1 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ACO1 Polyclonal Antibody at dilution 1:50
Rabbit Anti-ACO1 Polyclonal Antibody – Cat# MBS2518750

Immunohistochemistry (IHC) of anti-ACO1 antibody

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ACO1 Polyclonal Antibody at dilution 1:50
Rabbit Anti-ACO1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2518750

Other Notes

Small volumes of anti-ACO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACO1 purchase

MBS2518750 is an antibody targeting ACO1. Also known as ACO1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ACO1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
aconitate hydratase ACO1
NCBI Official Symbol
ACO1
NCBI Official Synonym Symbols
GLU1
UniProt Protein Name
Aconitate hydratase, mitochondrial
UniProt Synonym Protein Names
Citrate hydro-lyase
UniProt Gene Name
ACO1
UniProt Synonym Gene Names
GLU1; Aconitase
UniProt Entry Name
ACON_YEAST
NCBI Protein Information
aconitate hydratase ACO1

UniProt Comments for ACO1

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle. Can also provide minor contributions to the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. Plays also an essential role in mtDNA maintenance. May directly protect mtDNA from accumulation of point mutations and ssDNA breaks as a component of mitochondrial nucleoids, or by preventing accumulation of iron citrate thereby alleviating its detrimental effects in mitochondria.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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