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ADH1A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2519625

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
ADH1A, Polyclonal Antibody
Full Product Name
ADH1A Polyclonal Antibody
Product Gene Name
anti-ADH1A antibody
Product Synonym Names
ADH1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.7mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
39,859 Da
OMIM
103700
Immunogen
Recombinant protein of human ADH1A
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ADH1A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ADH1A antibody
WB: 1:500-1:2000
IHC: 1:25-1:100

Western Blot (WB) of anti-ADH1A antibody

Western Blot analysis of Human fetal liver and liver cancer tissue,Mouse liver and Human hepatocellular carcinoma tissue using ADH1A Polyclonal Antibody at dilution of 1:250
Rabbit Anti-ADH1A Polyclonal Antibody – Cat# MBS2519625

Immunohistochemistry (IHC) of anti-ADH1A antibody

Immunohistochemistry of paraffin-embedded Human lymphoma using ADH1A Polyclonal Antibody at dilution of 1:20
Rabbit Anti-ADH1A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2519625

Immunohistochemistry (IHC) of anti-ADH1A antibody

Immunohistochemistry of paraffin-embedded Human lung cancer using ADH1A Polyclonal Antibody at dilution of 1:20
Rabbit Anti-ADH1A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2519625

Other Notes

Small volumes of anti-ADH1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADH1A purchase

MBS2519625 is an antibody targeting ADH1A. Also known as ADH1A Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ADH1A. It may not necessarily be applicable to this product.

NCBI GI #
4501929
NCBI GeneID
124
NCBI Accession #
NP_000658.1
UniProt Secondary Accession #
Q17R68; A8K3E3
UniProt Related Accession #
P07327
GenBank Nucleotide #
NM_000667.3
NCBI Official Full Name
alcohol dehydrogenase 1A
NCBI Official Synonym Full Names
alcohol dehydrogenase 1A (class I), alpha polypeptide
NCBI Official Symbol
ADH1A
NCBI Official Synonym Symbols
ADH1
UniProt Protein Name
Alcohol dehydrogenase 1A
UniProt Synonym Protein Names
Alcohol dehydrogenase subunit alpha
UniProt Gene Name
ADH1A
UniProt Synonym Gene Names
ADH1
UniProt Entry Name
ADH1A_HUMAN
NCBI Protein Information
alcohol dehydrogenase 1A; ADH, alpha subunit; alcohol dehydrogenase 1 (class I), alpha polypeptide; alcohol dehydrogenase subunit alpha; aldehyde reductase

UniProt Comments for ADH1A

ADH1A: a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.1.1.1; Amino Acid Metabolism - tyrosine; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - metabolism by cytochrome P450; Lipid Metabolism - fatty acid; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Transcription regulation

Chromosomal Location of Human Ortholog: 4q23

Cellular Component: cytosol

Molecular Function: protein binding; zinc ion binding; alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent

Biological Process: xenobiotic metabolic process; alcohol metabolic process; drug metabolic process; ethanol oxidation
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Research Articles on ADH1A

1. Data indicate that the up-regulation of aldehyde dehydrogenase-1 (ALDH1) after neoadjuvant chemotherapy (NAC) predicts poor survival in locally advanced breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ADH1A antibody

 Products by Pathway  Pathway Diagram
 Abacavir Metabolism Pathway antibodies  Abacavir Metabolism Pathway Diagram
 Abacavir Transport And Metabolism Pathway antibodies  Abacavir Transport And Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway antibodies  Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway Diagram
 Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway antibodies  Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway Diagram
 Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway antibodies  Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway Diagram
 Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway antibodies  Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway Diagram
 Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway antibodies  Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway Diagram

Diseases associated with anti-ADH1A antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >3 publications with ADH1A and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with ADH1A and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with ADH1A and Carcinoma, Hepatocellular
 Ovarian Neoplasms Antibodies  >1 publications with ADH1A and Ovarian Neoplasms
 Recurrence Antibodies  >1 publications with ADH1A and Recurrence
 Necrosis Antibodies  >1 publications with ADH1A and Necrosis
 Poisoning Antibodies  >1 publications with ADH1A and Poisoning

Organs/Tissues associated with anti-ADH1A antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >10 publications with ADH1A and Liver
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