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CACNG5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8248088

MBS8248088 is an antibody targeting CACNG5. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to CACNG5 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CACNG5, Polyclonal Antibody
Full Product Name
Anti-CACNG5 Antibody
Product Gene Name
anti-CACNG5 antibody
Product Synonym Names
Voltage-dependent calcium channel gamma-5 subunit; Neuronal voltage-gated calcium channel gamma-5 subunit; Transmembrane AMPAR regulatory protein gamma-5; TARP gamma-5
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by affinity chromatography.
Specificity
Recognizes endogenous levels of CACNG5 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CACNG5 peptide (MBS8247800) is used for blocking the activity of CACNG5 antibody (MBS8248088)
Molecular Weight
30,903 Da
OMIM
606405
3D Structure
ModBase 3D Structure for Q9UF02
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CACNG5. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CACNG5 antibody
Western Blot (WB)
Application Notes for anti-CACNG5 antibody
WB: 1/500 - 1/2000

Western Blot (WB) of anti-CACNG5 antibody

Western blot analysis of CACNG5 expression in HepG2 (A), mouse liver (B), RAW264.7 whole cell lysates.
Rabbit Anti-CACNG5 Polyclonal Antibody – Cat# MBS8248088

Other Notes

Small volumes of anti-CACNG5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CACNG5. It may not necessarily be applicable to this product.

NCBI GI #
22027551
NCBI GeneID
27091
NCBI Accession #
NP_665810.1
UniProt Primary Accession #
Q9UF02
UniProt Secondary Accession #
Q547R3; Q8WXS7; Q9UHM3; A8K2A6
UniProt Related Accession #
Q9UF02
GenBank Nucleotide #
NM_145811.2
NCBI Official Full Name
voltage-dependent calcium channel gamma-5 subunit
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit gamma 5
NCBI Official Symbol
CACNG5
UniProt Protein Name
Voltage-dependent calcium channel gamma-5 subunit
UniProt Synonym Protein Names
Neuronal voltage-gated calcium channel gamma-5 subunit; Transmembrane AMPAR regulatory protein gamma-5; TARP gamma-5
Protein Family
Voltage-dependent calcium channel
UniProt Gene Name
CACNG5
UniProt Synonym Gene Names
TARP gamma-5
UniProt Entry Name
CCG5_HUMAN
NCBI Protein Information
voltage-dependent calcium channel gamma-5 subunit

NCBI Summary for CACNG5

The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]
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UniProt Comments for CACNG5

CACNG5: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: plasma membrane; postsynaptic density

Molecular Function: channel regulator activity; ion transmembrane transporter activity; voltage-gated calcium channel activity

Biological Process: transmission of nerve impulse; transport
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Research Articles on CACNG5

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CACNG5 antibody

 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Cardiac Conduction Pathway antibodies  Cardiac Conduction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram

Organs/Tissues associated with anti-CACNG5 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with CACNG5 and Brain
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