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CADM3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153452

MBS153452 is an antibody targeting CADM3. Also known as CADM3 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CADM3, Polyclonal Antibody
Full Product Name
CADM3 Antibody
Product Gene Name
Product Synonym Names
Cell adhesion molecule 3; BIgR; NECL1; Necl-1; TSLL1; IGSF4B; synCAM3; cell adhesion molecule 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid ; CADM3 antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
CADM3 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
CADM3 antibody is human, mouse and rat reactive. At least three isoforms are known to exist; this antibody will only detect the two longest isoforms. CADM3 antibody is predicted to not cross-react with other members of the CADM protein family.
Preparation and Storage
CADM3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Molecular Weight
Predicted: 44; 48 kDa

Observed: 44 kDa
OMIM
609743
3D Structure
ModBase 3D Structure for Q8N126
Immunogen
CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3.The immunogen is located within amino acids 220 - 270 of CADM3.
Applications Tested/Suitable for anti-CADM3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC-p), Immunofluorescence (IF)
Application Notes for anti-CADM3 antibody
CADM3 antibody can be used for detection of CADM3 by Western blot at 1 - 2 ug/ml. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
Optimal dilutions for each application to be determined by the researcher.

Western Blot (WB) of anti-CADM3 antibody

Western blot analysis of CADM3 in human brain tissue lysate with CADM3 antibody at (A) 1 and (B) 2 μg/ml.
Rabbit Anti-CADM3 Polyclonal Antibody – Cat# MBS153452

Immunohistochemistry (IHC) of anti-CADM3 antibody

Immunohistochemistry of CADM3 in mouse brain tissue with CADM3 antibody at 5 μg/ml.
Rabbit Anti-CADM3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153452

Immunofluorescence (IF) of anti-CADM3 antibody

Immunofluorescence of CADM3 in mouse brain tissue with CADM3 antibody at 20 μg/ml.
Rabbit Anti-CADM3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153452

Other Notes

Small volumes of anti-CADM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CADM3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cell adhesion molecule 3 isoform 1
NCBI Official Synonym Full Names
cell adhesion molecule 3
NCBI Official Symbol
CADM3
NCBI Official Synonym Symbols
BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3
UniProt Protein Name
Cell adhesion molecule 3
UniProt Synonym Protein Names
Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1
UniProt Gene Name
CADM3
UniProt Synonym Gene Names
IGSF4B; NECL1; SYNCAM3; TSLL1; IgSF4B; NECL-1; SynCAM3; TSLL1
UniProt Entry Name
CADM3_HUMAN
NCBI Protein Information
cell adhesion molecule 3; TSLC1-like 1; nectin-like 1; TSLC1-like protein 1; nectin-like protein 1; brain immunoglobulin receptor; synaptic cell adhesion molecule 3; immunoglobulin superfamily member 4B; immunoglobulin superfamily, member 4B; dendritic cell nectin-like protein 1 short isoform

NCBI Summary for CADM3

IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008]

UniProt Comments for CADM3

CADM3: Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 1q21.2-q22

Cellular Component: integral to membrane; plasma membrane; intercellular junction

Molecular Function: protein homodimerization activity

Biological Process: heterophilic cell adhesion; intercellular junction assembly and maintenance; protein localization; homophilic cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CADM3 antibody

 Reference Product  PubMed Publications
 CADM1 antibody  >4 publications with CADM3 and CADM1
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