• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CAMK4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8241951

MBS8241951 is an antibody targeting CAMK4. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to CaMK4 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CaMK4, Polyclonal Antibody
Full Product Name
Anti-CaMK4 Antibody
Product Gene Name
anti-CAMK4 antibody
Product Synonym Names
CAMK; CAMK-GR; CAMKIV; Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CaM kinase-GR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% Sodium Azide.
Purity/Purification
The antibody was purified by affinity chromatography.
Specificity
Recognizes endogenous levels of CaMK4 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CaMK4 peptide (MBS8243893) is used for blocking the activity of CaMK4 antibody (MBS8241951)
Molecular Weight
51,926 Da
OMIM
114080
3D Structure
ModBase 3D Structure for Q16566
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CaMK4. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CAMK4 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-CAMK4 antibody
Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200); Immunofluorescence/Immunocytochemistry: (1/100 - 1/500)

Western Blot (WB) of anti-CAMK4 antibody

Western blot analysis of CaMK4 expression in Jurkat (A), K562 (B) whole cell lysates.
Rabbit Anti-CAMK4 Polyclonal Antibody – Cat# MBS8241951

Immunohistochemistry (IHC) of anti-CAMK4 antibody

Immunohistochemical analysis of CaMK4 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-CAMK4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS8241951

Immunofluorescence (IF) of anti-CAMK4 antibody

Immunofluorescent analysis of CaMK4 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Rabbit Anti-CAMK4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS8241951

Other Notes

Small volumes of anti-CAMK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CAMK4. It may not necessarily be applicable to this product.

NCBI GI #
2499586
NCBI GeneID
814
NCBI Accession #
Q16566.1
UniProt Primary Accession #
Q16566
UniProt Secondary Accession #
D3DSZ7
UniProt Related Accession #
Q16566
NCBI Official Full Name
Calcium/calmodulin-dependent protein kinase type IV
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase IV
NCBI Official Symbol
CAMK4
NCBI Official Synonym Symbols
caMK; CaMK IV; CaMK-GR
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type IV
UniProt Synonym Protein Names
CaM kinase-GR
Protein Family
Calcium/calmodulin-dependent protein kinase
UniProt Gene Name
CAMK4
UniProt Synonym Gene Names
CAMK; CAMK-GR; CAMKIV; CaMK IV
UniProt Entry Name
KCC4_HUMAN
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type IV

NCBI Summary for CAMK4

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for CAMK4

CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described.

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.17; Kinase, protein; CAMK group; CAMK1 family

Chromosomal Location of Human Ortholog: 5q21.3

Cellular Component: cytoplasm; cytosol; nucleolus; nucleoplasm

Molecular Function: ATP binding; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; calmodulin-dependent protein kinase activity

Biological Process: adaptive immune response; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; inflammatory response; innate immune response; long-term memory; myeloid dendritic cell cytokine production; myeloid dendritic cell differentiation; nerve growth factor receptor signaling pathway; nerve-nerve synaptic transmission; nucleocytoplasmic transport; peptidyl-serine phosphorylation; phospholipase C activation; positive regulation of protein export from nucleus; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of osteoclast differentiation; regulation of T cell differentiation in the thymus; signal transduction; synaptic transmission
Show more

Research Articles on CAMK4

1. Expression of CaMKIV inhibits autophosphorylation and activation of CaMKII, and elicits G0/G1cell cycle arrest,impairing cell proliferation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CAMK4 antibody

 Reference Product  PubMed Publications
 CREB1 antibody  >8 publications with CAMK4 and CREB1
 CREBBP antibody  >6 publications with CAMK4 and CREBBP
 CAMKK2 antibody  >6 publications with CAMK4 and CAMKK2
 MEF2A antibody  >2 publications with CAMK4 and MEF2A
 CAMKK1 antibody  >2 publications with CAMK4 and CAMKK1
 ATF2 antibody  >2 publications with CAMK4 and ATF2
 CABIN1 antibody  >1 publications with CAMK4 and CABIN1
 HDAC4 antibody  >1 publications with CAMK4 and HDAC4
 STMN1 antibody  >1 publications with CAMK4 and STMN1
 MEF2D antibody  >1 publications with CAMK4 and MEF2D

Pathways associated with anti-CAMK4 antibody

 Products by Pathway  Pathway Diagram
 Activation Of CaMK IV Pathway antibodies  Activation Of CaMK IV Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 CREB Phosphorylation Through The Activation Of CaMKK Pathway antibodies  CREB Phosphorylation Through The Activation Of CaMKK Pathway Diagram

Diseases associated with anti-CAMK4 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >24 publications with CAMK4 and Nervous System Diseases
 Brain Diseases Antibodies  >14 publications with CAMK4 and Brain Diseases
 Cardiovascular Diseases Antibodies  >13 publications with CAMK4 and Cardiovascular Diseases
 Mental Disorders Antibodies  >11 publications with CAMK4 and Mental Disorders
 Pain Antibodies  >10 publications with CAMK4 and Pain
 Inflammation Antibodies  >8 publications with CAMK4 and Inflammation
 Memory Disorders Antibodies  >8 publications with CAMK4 and Memory Disorders
 Hypertrophy Antibodies  >7 publications with CAMK4 and Hypertrophy
 Learning Disorders Antibodies  >6 publications with CAMK4 and Learning Disorders
 Necrosis Antibodies  >6 publications with CAMK4 and Necrosis

Organs/Tissues associated with anti-CAMK4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >137 publications with CAMK4 and Brain
 Blood Antibodies  >44 publications with CAMK4 and Blood
 Muscle Antibodies  >21 publications with CAMK4 and Muscle
 Testis Antibodies  >13 publications with CAMK4 and Testis
 Thymus Antibodies  >10 publications with CAMK4 and Thymus
 Kidney Antibodies  >9 publications with CAMK4 and Kidney
 Spleen Antibodies  >6 publications with CAMK4 and Spleen
 Liver Antibodies  >3 publications with CAMK4 and Liver
 Skin Antibodies  >3 publications with CAMK4 and Skin
 Lymph Node Antibodies  >1 publications with CAMK4 and Lymph Node
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000