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CHKA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8569725

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CHKA, Polyclonal Antibody
Full Product Name
CHKA Polyclonal Antibody
Product Gene Name
anti-CHKA antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
50kDa; 52kDa
OMIM
118491
3D Structure
ModBase 3D Structure for P35790
Immunogen
Recombinant protein of human CHKA (NP_001268.2).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CHKA antibody
Western Blot (WB)
Application Notes for anti-CHKA antibody
WB: 1:500-1:2000

Other Notes

Small volumes of anti-CHKA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHKA purchase

MBS8569725 is an antibody targeting CHKA. Also known as CHKA Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CHKA. It may not necessarily be applicable to this product.

NCBI GI #
226694197
NCBI GeneID
1119
NCBI Accession #
P35790.3
UniProt Primary Accession #
P35790
UniProt Related Accession #
P35790
NCBI Official Full Name
Choline kinase alpha
NCBI Official Synonym Full Names
choline kinase alpha
NCBI Official Symbol
CHKA
NCBI Official Synonym Symbols
CK; EK; CHK; CKI
UniProt Protein Name
Choline kinase alpha
UniProt Synonym Protein Names
CHETK-alpha; Ethanolamine kinase (EC:2.7.1.82); EK
Protein Family
Choline kinase
UniProt Gene Name
CHKA
UniProt Synonym Gene Names
CHK; CKI; CK; EK
UniProt Entry Name
CHKA_HUMAN
NCBI Protein Information
choline kinase alpha

UniProt Comments for CHKA

CHKA: Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. Belongs to the choline/ethanolamine kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - glycerophospholipid; EC 2.7.1.82; Kinase, other; EC 2.7.1.32

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cytosol

Molecular Function: choline binding; signal transducer activity; protein homodimerization activity; cholinesterase activity; drug binding; ethanolamine kinase activity; choline kinase activity; ATP binding

Biological Process: choline metabolic process; CDP-choline pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; lipid metabolic process; signal transduction; lipid transport; phosphorylation
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Research Articles on CHKA

1. miR-876-5p was able to significantly decrease the expression level of choline kinase alpha mRNA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CHKA antibody

 Reference Product  PubMed Publications
 PCYT1A antibody  >5 publications with CHKA and PCYT1A

Pathways associated with anti-CHKA antibody

 Products by Pathway  Pathway Diagram
 Acetylcholine Synthesis Pathway antibodies  Acetylcholine Synthesis Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Phosphatidylcholine (PC) Biosynthesis, Choline => PC Pathway antibodies  Phosphatidylcholine (PC) Biosynthesis, Choline => PC Pathway Diagram

Diseases associated with anti-CHKA antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with CHKA and Nervous System Diseases
 Liver Neoplasms Antibodies  >3 publications with CHKA and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with CHKA and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with CHKA and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with CHKA and Cell Transformation, Neoplastic
 Weight Loss Antibodies  >1 publications with CHKA and Weight Loss
 Kidney Diseases Antibodies  >1 publications with CHKA and Kidney Diseases
 Fatty Liver Antibodies  >1 publications with CHKA and Fatty Liver
 Inflammation Antibodies  >1 publications with CHKA and Inflammation
 Hyperplasia Antibodies  >1 publications with CHKA and Hyperplasia

Organs/Tissues associated with anti-CHKA antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >11 publications with CHKA and Lung
 Blood Antibodies  >9 publications with CHKA and Blood
 Intestine Antibodies  >7 publications with CHKA and Intestine
 Muscle Antibodies  >7 publications with CHKA and Muscle
 Kidney Antibodies  >7 publications with CHKA and Kidney
 Bone Antibodies  >6 publications with CHKA and Bone
 Prostate Antibodies  >4 publications with CHKA and Prostate
 Embryonic Tissue Antibodies  >4 publications with CHKA and Embryonic Tissue
 Stomach Antibodies  >3 publications with CHKA and Stomach
 Bladder Antibodies  >3 publications with CHKA and Bladder
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