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DNAL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8588232

This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in… More details

$400 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
DNAL1, Polyclonal Antibody
Full Product Name
DNAL1 Antibody
Product Gene Name
Product Synonym Names
C14orf168; dynein light chain 1; axonemal
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
The antibody detects endogenous levels of total DNAL1 protein.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
21,533 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (74111578..74170431). Location: 14q24.3
OMIM
610062
3D Structure
ModBase 3D Structure for Q4LDG9
Immunogen
Synthesized peptide derived from internal of human DNAL1.

Product Categories/Family for anti-DNAL1 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DNAL1 antibody
Western Blot (WB)
Application Notes for anti-DNAL1 antibody
WB: 1:500~1:3000

Product References and Citations for anti-DNAL1 antibody

Horvath J., Am. J. Respir. Cell Mol. Biol. 33:41-47 (2005).The German cDNA consortium; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.The MGC Project Team; Genome Res. 14:2121-2127 (2004)

Other Notes

Small volumes of anti-DNAL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNAL1 purchase

MBS8588232 is an antibody targeting DNAL1. Also known as DNAL1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dynein light chain 1, axonemal isoform 2
NCBI Official Synonym Full Names
dynein, axonemal, light chain 1
NCBI Official Symbol
DNAL1
NCBI Official Synonym Symbols
CILD16; C14orf168
UniProt Protein Name
Dynein light chain 1, axonemal
Protein Family
UniProt Gene Name
DNAL1
UniProt Synonym Gene Names
C14orf168
UniProt Entry Name
DNAL1_HUMAN
NCBI Protein Information
dynein light chain 1, axonemal

UniProt Comments for DNAL1

DNAL1: Defects in DNAL1 are the cause of primary ciliary dyskinesia type 16 (CILD16). A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the dynein light chain LC1-type family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q24.3

Disease: Ciliary Dyskinesia, Primary, 16
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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