Rabbit Anti-DNASE1L1 Polyclonal Antibody – Cat# MBS9125409

Western blot analysis of extracts of MCF7 cells, using DNASE1L1 Antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.

DNASE1L1 Antibody – Rabbit Polyclonal

Name: DNASE1L1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9125409
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9125409

This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized. More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DNASE1L1, Polyclonal Antibody

Full Product Name

DNASE1L1 Polyclonal Antibody

Product Gene Name

anti-DNASE1L1 antibody

Product Synonym Names

XIB; G4.8; DNL1L; DNASEX; DNAS1L1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

302

OMIM

300081

3D Structure

ModBase 3D Structure for P49184

Species

Human

Immunogen

Recombinant protein of human DNASE1L1

Calculated Molecular Weight

34kDa

Product Categories/Family for anti-DNASE1L1 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-DNASE1L1 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes for anti-DNASE1L1 antibody

WB: 1:200-1:2000
IHC: 1:50-1:200
IF: 1:50-1:100

Other Notes

Small volumes of anti-DNASE1L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNASE1L1 purchase

MBS9125409 is an antibody targeting DNASE1L1. Also known as DNASE1L1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DNASE1L1. It may not necessarily be applicable to this product.

NCBI GI #

1352319

NCBI GeneID

1774

NCBI Accession #

P49184.1

UniProt Primary Accession #

P49184

UniProt Secondary Accession #

Q5HY41; D3DWW7

UniProt Related Accession #

P49184

NCBI Official Full Name

Deoxyribonuclease-1-like 1

NCBI Official Synonym Full Names

deoxyribonuclease I-like 1

NCBI Official Symbol

DNASE1L1

NCBI Official Synonym Symbols

XIB; G4.8; DNL1L; DNASEX; DNAS1L1

UniProt Protein Name

Deoxyribonuclease-1-like 1

UniProt Synonym Protein Names

DNase X; Deoxyribonuclease I-like 1; DNase I-like 1; Muscle-specific DNase I-like; XIB

Protein Family

Deoxyribonuclease

UniProt Gene Name

DNASE1L1

UniProt Synonym Gene Names

DNAS1L1; DNL1L; DNase I-like 1

UniProt Entry Name

DNSL1_HUMAN

NCBI Protein Information

deoxyribonuclease-1-like 1; DNase I-like 1; DNase I, lysosomal-like; DNase I-like, muscle-specific

NCBI Summary for DNASE1L1

This gene encodes a deoxyribonuclease protein that shows high sequence similarity to DNase I. The encoded protein is localized to the endoplasmic reticulum and modified by N-linked glycosylation. Alternate transcriptional splice variants encoding the same protein have been observed. [provided by RefSeq, Jan 2015]

UniProt Comments for DNASE1L1

DNASE1L1: a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]

Protein type: Deoxyribonuclease; EC 3.1.21.-

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: endoplasmic reticulum; nucleus

Molecular Function: endodeoxyribonuclease activity, producing 5'-phosphomonoesters; DNA binding; deoxyribonuclease activity; endodeoxyribonuclease activity

Biological Process: DNA catabolic process, endonucleolytic; DNA metabolic process

Research Articles on DNASE1L1

1. genotyping of all 21 nonsynonymous DNase 1L1 SNPs was performed in 16 populations representing 3 ethnic groups; 2 activity-abolishing and 4 activity-reducing SNPs were confirmed to be functional; may be plausible that a minor allele of 6 SNPs producing a loss-of-function or low-activity variant could serve as a risk factor for disease

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-DNASE1L1 antibody

Disease Name	Pubmed Publications
Recurrence Antibodies	>1 publications with DNASE1L1 and Recurrence
Breast Neoplasms Antibodies	>1 publications with DNASE1L1 and Breast Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with DNASE1L1 and Neoplasm Metastasis

Organs/Tissues associated with anti-DNASE1L1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with DNASE1L1 and Blood
Heart Antibodies	>2 publications with DNASE1L1 and Heart
Lymph Antibodies	>1 publications with DNASE1L1 and Lymph
Mouth Antibodies	>1 publications with DNASE1L1 and Mouth
Lung Antibodies	>1 publications with DNASE1L1 and Lung
Lymph Node Antibodies	>1 publications with DNASE1L1 and Lymph Node
Prostate Antibodies	>1 publications with DNASE1L1 and Prostate