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ENDOG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821345

MBS821345 is an antibody targeting ENDOG. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to ENDOG More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ENDOG, Polyclonal Antibody
Full Product Name
Anti-ENDOG Antibody
Product Gene Name
Product Synonym Names
Endonuclease G, mitochondrial; Endo G
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of ENDOG protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
ENDOG peptide (MBS824404) is used for blocking the activity of ENDOG antibody (MBS821345)
Molecular Weight
32,620 Da
OMIM
600440
3D Structure
ModBase 3D Structure for Q14249
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ENDOG. The exact sequence is proprietary.
Applications Tested/Suitable for anti-ENDOG antibody
Western Blot (WB)
Application Notes for anti-ENDOG antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-ENDOG antibody

Western blot analysis of ENDOG expression in NCIH292 (A), HepG2 (B), Raw264.7 (C), PC12 (D) whole cell lysates.
Rabbit Anti-ENDOG Polyclonal Antibody – Cat# MBS821345

Other Notes

Small volumes of anti-ENDOG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ENDOG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endonuclease G, mitochondrial
NCBI Official Synonym Full Names
endonuclease G
NCBI Official Symbol
ENDOG
UniProt Protein Name
Endonuclease G, mitochondrial
Protein Family
UniProt Gene Name
ENDOG
UniProt Synonym Gene Names
Endo G
UniProt Entry Name
NUCG_HUMAN
NCBI Protein Information
endonuclease G, mitochondrial; endo G; mitochondrial endonuclease G

NCBI Summary for ENDOG

The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008]
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UniProt Comments for ENDOG

ENDOG: Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. Homodimer. Belongs to the DNA/RNA non-specific endonuclease family.

Protein type: Ribonuclease; Deoxyribonuclease; Apoptosis; EC 3.1.30.-; Mitochondrial

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: mitochondrion

Molecular Function: protein binding; nuclease activity; nucleic acid binding; endonuclease activity; metal ion binding

Biological Process: response to antibiotic; positive regulation of apoptosis; in utero embryonic development; DNA fragmentation during apoptosis; DNA recombination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ENDOG antibody

 Reference Product  PubMed Publications
 AIFM1 antibody  >5 publications with ENDOG and AIFM1
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