Rabbit Anti-ENTPD1 Polyclonal Antibody – Cat# MBS9451707

ENTPD1 Antibody – Rabbit Polyclonal

Name: ENTPD1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9451707
Price: 435 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9451707

In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ENTPD1, Polyclonal Antibody

Full Product Name

ENTPD1 Conjugated Antibody

Product Gene Name

anti-ENTPD1 antibody

Product Synonym Names

CD39; SPG64; ATPDase; NTPDase-1

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

Specificity

The antibody detects endogenous levels of total ENTPD1 protein.

Preparation and Storage

Store at 4 degree C for 6 months.

Molecular Weight

56kDa

OMIM

601752

3D Structure

ModBase 3D Structure for P49961

Immunogen

Synthetic peptide of human ENTPD1

Conjugation

Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

Excitation Emission

AF350: 346nm/442nm

Applications Tested/Suitable for anti-ENTPD1 antibody

Most Applications

Application Notes for anti-ENTPD1 antibody

Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-ENTPD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENTPD1 purchase

MBS9451707 is an antibody targeting ENTPD1. Also known as ENTPD1 Conjugated Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ENTPD1. It may not necessarily be applicable to this product.

NCBI GI #

45580700

NCBI GeneID

953

NCBI Accession #

NP_001767

UniProt Primary Accession #

P49961

UniProt Related Accession #

P49961

GenBank Nucleotide #

NM_001776

NCBI Official Full Name

ectonucleoside triphosphate diphosphohydrolase 1 isoform 1

NCBI Official Synonym Full Names

ectonucleoside triphosphate diphosphohydrolase 1

NCBI Official Symbol

ENTPD1

NCBI Official Synonym Symbols

CD39; SPG64; ATPDase; NTPDase-1

UniProt Protein Name

Ectonucleoside triphosphate diphosphohydrolase 1

UniProt Synonym Protein Names

Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen

Protein Family

Ectonucleoside triphosphate diphosphohydrolase

UniProt Gene Name

ENTPD1

UniProt Synonym Gene Names

CD39; NTPDase 1; Ecto-ATPDase 1

UniProt Entry Name

ENTP1_HUMAN

NCBI Protein Information

ectonucleoside triphosphate diphosphohydrolase 1

NCBI Summary for ENTPD1

The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

UniProt Comments for ENTPD1

ENTPD1: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; EC 3.6.1.5; Extracellular matrix; Nucleotide Metabolism - pyrimidine; Membrane protein, multi-pass; Hydrolase

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: membrane; integral to plasma membrane; plasma membrane; basal lamina

Molecular Function: protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: platelet activation; G-protein coupled receptor protein signaling pathway; purine ribonucleoside diphosphate catabolic process; cell adhesion; blood coagulation

Disease: Spastic Paraplegia 64, Autosomal Recessive

Research Articles on ENTPD1

1. Changes in the local expression and activity of CD39 and CD73 in calcified valves suggest their potential role in calcific aortic valve disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.