• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

EPCAM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2529227

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EPCAM, Polyclonal Antibody
Full Product Name
EPCAM Polyclonal Antibody
Product Gene Name
anti-EPCAM antibody
Product Synonym Names
ESA, KSA, M4S1, MK-1, DIAR5, EGP-2, EGP40, KS1/4, MIC18, TROP1, EGP314, HNPCC8, TACSTD1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.8mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
34,932 Da
OMIM
185535
Immunogen
Synthetic peptide of human EPCAM
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-EPCAM antibody

Epigenetics
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EPCAM antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-EPCAM antibody
IHC: 1:25-1:100

Immunohistochemistry (IHC) of anti-EPCAM antibody

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using EPCAM Polyclonal Antibody at dilution 1:25
Rabbit Anti-EPCAM Polyclonal Antibody – Cat# MBS2529227

Other Notes

Small volumes of anti-EPCAM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPCAM purchase

MBS2529227 is an antibody targeting EPCAM. Also known as EPCAM Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EPCAM. It may not necessarily be applicable to this product.

NCBI GI #
218505670
NCBI GeneID
4072
NCBI Accession #
NP_002345.2
UniProt Secondary Accession #
P18180; Q6FG26; Q6FG49; Q96C47; Q9UCD0
UniProt Related Accession #
P16422
GenBank Nucleotide #
NM_002354.2
NCBI Official Full Name
epithelial cell adhesion molecule
NCBI Official Synonym Full Names
epithelial cell adhesion molecule
NCBI Official Symbol
EPCAM
NCBI Official Synonym Symbols
ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
UniProt Protein Name
Epithelial cell adhesion molecule
UniProt Synonym Protein Names
Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; CD_antigen: CD326
Protein Family
Epithelial cell adhesion molecule
UniProt Gene Name
EPCAM
UniProt Synonym Gene Names
GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; Ep-CAM; EGP; EGP314; hEGP314
UniProt Entry Name
EPCAM_HUMAN
NCBI Protein Information
epithelial cell adhesion molecule; adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; epithelial glycoprotein 314; human epithelial glycoprotein-2; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); tumor-associated calcium signal transducer 1

UniProt Comments for EPCAM

EPCAM: a single-pass type I membrane protein of the EPCAM family. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas including pancreatic carcinoma. May be a marker of cancer stem cells.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: cell surface; tight junction; basolateral plasma membrane; apical plasma membrane; plasma membrane; integral to membrane; lateral plasma membrane

Molecular Function: protein binding; protein complex binding

Biological Process: ureteric bud development; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation

Disease: Diarrhea 5, With Tufting Enteropathy, Congenital; Colorectal Cancer, Hereditary Nonpolyposis, Type 8
Show more

Research Articles on EPCAM

1. The overexpression of EpCAM in the stroma of intrahepatic cholangiocarcinoma is an independent risk factor for overall and disease-free survival; the overexpression of EpCAM in nontumor fibrous liver tissue is closely correlated with a worst disease-free survival

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EPCAM antibody

 Reference Product  PubMed Publications
 CD44 antibody  >155 publications with EPCAM and CD44
 CLDN7 antibody  >15 publications with EPCAM and CLDN7
 CDH1 antibody  >13 publications with EPCAM and CDH1
 KRT19 antibody  >11 publications with EPCAM and KRT19
 TSPAN8 antibody  >6 publications with EPCAM and TSPAN8

Diseases associated with anti-EPCAM antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >590 publications with EPCAM and Carcinoma
 Neoplasm Metastasis Antibodies  >341 publications with EPCAM and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >262 publications with EPCAM and Adenocarcinoma
 Breast Neoplasms Antibodies  >208 publications with EPCAM and Breast Neoplasms
 Liver Diseases Antibodies  >160 publications with EPCAM and Liver Diseases
 Liver Neoplasms Antibodies  >159 publications with EPCAM and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >134 publications with EPCAM and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >108 publications with EPCAM and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >88 publications with EPCAM and Ovarian Neoplasms
 Carcinoma, Squamous Cell Antibodies  >85 publications with EPCAM and Carcinoma, Squamous Cell

Organs/Tissues associated with anti-EPCAM antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >460 publications with EPCAM and Blood
 Liver Antibodies  >276 publications with EPCAM and Liver
 Lung Antibodies  >177 publications with EPCAM and Lung
 Prostate Antibodies  >105 publications with EPCAM and Prostate
 Lymph Node Antibodies  >70 publications with EPCAM and Lymph Node
 Ascites Antibodies  >57 publications with EPCAM and Ascites
 Vascular Antibodies  >56 publications with EPCAM and Vascular
 Stomach Antibodies  >56 publications with EPCAM and Stomach
 Intestine Antibodies  >51 publications with EPCAM and Intestine
 Kidney Antibodies  >44 publications with EPCAM and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000