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EPHA6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2559713

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EPHA6, Polyclonal Antibody
Full Product Name
EPHA6 Polyclonal Antibody
Product Gene Name
anti-EPHA6 antibody
Product Synonym Names
Ehk 2; EHK-2; Ehk2; EPH homology kinase 2; Eph Receptor A6; Epha6; EPHA6; Ephrin receptor EphA6; Ephrin type A receptor 6; Ephrin type-A receptor 6; Hek12
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.8mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
116 kDa
OMIM
600066
3D Structure
ModBase 3D Structure for Q9UF33
Immunogen
Synthetic peptide of human EPHA6
Conjugation
Unconjugated

Product Categories/Family for anti-EPHA6 antibody

Cardiovascular; Neuroscience
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EPHA6 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-EPHA6 antibody
WB: 1:500-1:2000
IHC: 1:30-1:150
ELISA: 1:5000-1:10000

Western Blot (WB) of anti-EPHA6 antibody

Western blot analysis of 293T cell Human testis tissue lysate A549 cell lysates using EPHA6 Polyclonal Antibody at dilution of 1:800
Rabbit Anti-EPHA6 Polyclonal Antibody – Cat# MBS2559713

Immunohistochemistry (IHC) of anti-EPHA6 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using EPHA6 Polyclonal Antibody at dilution of 1:40(×200)
Rabbit Anti-EPHA6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2559713

Immunohistochemistry (IHC) of anti-EPHA6 antibody

Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using EPHA6 Polyclonal Antibody at dilution of 1:40(×200)
Rabbit Anti-EPHA6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2559713

Other Notes

Small volumes of anti-EPHA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPHA6 purchase

MBS2559713 is an antibody targeting EPHA6. Also known as EPHA6 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EPHA6. It may not necessarily be applicable to this product.

NCBI GI #
27734955
NCBI GeneID
285220
NCBI Accession #
NP_775926.1
UniProt Primary Accession #
Q9UF33
UniProt Related Accession #
Q9UF33
GenBank Nucleotide #
NP_775926.1
NCBI Official Full Name
ephrin type-A receptor 6 isoform b
NCBI Official Synonym Full Names
EPH receptor A6
NCBI Official Symbol
EPHA6
NCBI Official Synonym Symbols
EHK2; EK12; EPA6; EHK-2; HEK12; PRO57066
UniProt Protein Name
Ephrin type-A receptor 6
UniProt Synonym Protein Names
EPH homology kinase 2; EHK-2; EPH-like kinase 12
Protein Family
Ephrin type-A receptor
UniProt Gene Name
EPHA6
UniProt Synonym Gene Names
EHK2; HEK12; EHK-2; EK12
UniProt Entry Name
EPHA6_HUMAN
NCBI Protein Information
ephrin type-A receptor 6

UniProt Comments for EPHA6

EphA6: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, TK; Protein kinase, tyrosine (receptor); Kinase, protein; EC 2.7.10.1; Membrane protein, integral; TK group; Eph family

Chromosomal Location of Human Ortholog: 3q11.2

Cellular Component: nucleoplasm; integral to plasma membrane; plasma membrane

Molecular Function: ephrin receptor activity; ATP binding

Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; ephrin receptor signaling pathway
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Research Articles on EPHA6

1. The EPHA6 rs4857055 C > T SNP is a novel candidate gene for hypertension in the Korean population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EPHA6 antibody

 Reference Product  PubMed Publications
 EFNA1 antibody  >1 publications with EPHA6 and EFNA1

Pathways associated with anti-EPHA6 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 EPHA Forward Signaling Pathway antibodies  EPHA Forward Signaling Pathway Diagram
 EphrinA-EPHA Pathway antibodies  EphrinA-EPHA Pathway Diagram

Diseases associated with anti-EPHA6 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with EPHA6 and Necrosis
 Inflammation Antibodies  >1 publications with EPHA6 and Inflammation
 Learning Disorders Antibodies  >1 publications with EPHA6 and Learning Disorders
 Disease Models, Animal Antibodies  >1 publications with EPHA6 and Disease Models, Animal
 Congenital Abnormalities Antibodies  >1 publications with EPHA6 and Congenital Abnormalities

Organs/Tissues associated with anti-EPHA6 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >12 publications with EPHA6 and Brain
 Kidney Antibodies  >1 publications with EPHA6 and Kidney
 Prostate Antibodies  >1 publications with EPHA6 and Prostate
 Testis Antibodies  >1 publications with EPHA6 and Testis
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