HES-5 Antibody – Rabbit Polyclonal

HES5: Transcriptional repressor of genes that require a bHLH protein for their transcription.

Protein type: Cell development/differentiation; Transcription regulation

Cellular Component: nucleus

Molecular Function: protein dimerization activity; protein binding; DNA binding; double-stranded DNA binding; chromatin binding; transcription factor binding

Biological Process: transcription from RNA polymerase II promoter; neural tube development; radial glial cell differentiation in the forebrain; regulation of myelination; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; multicellular organismal development; cell maturation; positive regulation of JAK-STAT cascade; auditory receptor cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of neurogenesis; regulation of transcription, DNA-dependent; astrocyte differentiation; regulation of cell differentiation; positive regulation of cell proliferation; chondrocyte differentiation; protein complex assembly; oligodendrocyte development; cell adhesion; cell differentiation; positive regulation of BMP signaling pathway; positive regulation of Notch signaling pathway; nervous system development; Notch signaling pathway; smoothened signaling pathway; camera-type eye development; transcription, DNA-dependent; auditory receptor cell fate determination; myelination in the central nervous system; negative regulation of oligodendrocyte differentiation; telencephalon development; negative regulation of neuron differentiation; glial cell fate commitment; cartilage development; negative regulation of astrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; brain development; negative regulation of transcription, DNA-dependent