Rabbit Anti-IL11 Polyclonal Antibody – Cat# MBS9128570

Immunohistochemistry of paraffin-embedded human stomach using IL11 antibody at dilution of 1:100 (40x lens).

IL11 Antibody – Rabbit Polyclonal

Name: IL11 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9128570
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9128570

The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL11, Polyclonal Antibody

Full Product Name

IL11 Polyclonal Antibody

Product Gene Name

anti-IL11 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Preparation and Storage

Store at -20 degree C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

21kDa

OMIM

147681

3D Structure

ModBase 3D Structure for P20809

Immunogen

Recombinant protein of human IL11

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-IL11 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-IL11 antibody

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Other Notes

Small volumes of anti-IL11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL11 purchase

MBS9128570 is an antibody targeting IL11. Also known as IL11 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL11. It may not necessarily be applicable to this product.

NCBI GI #

10834994

NCBI GeneID

3589

NCBI Accession #

NP_000632.1

UniProt Primary Accession #

P20809

UniProt Secondary Accession #

Q96EB4; B4DQV5

UniProt Related Accession #

P20809

GenBank Nucleotide #

NM_000641.3

NCBI Official Full Name

interleukin-11 isoform 1

NCBI Official Synonym Full Names

interleukin 11

NCBI Official Symbol

IL11

NCBI Official Synonym Symbols

AGIF; IL-11

UniProt Protein Name

Interleukin-11

UniProt Synonym Protein Names

Adipogenesis inhibitory factor

Protein Family

Interleukin

UniProt Gene Name

IL11

UniProt Synonym Gene Names

AGIF

UniProt Entry Name

IL11_HUMAN

NCBI Protein Information

interleukin-11

UniProt Comments for IL11

IL11: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Belongs to the IL-6 superfamily.

Protein type: Cell cycle regulation; Cytokine; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: growth factor activity; cytokine activity; interleukin-11 receptor binding

Biological Process: fat cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of MAPKKK cascade; cell-cell signaling; megakaryocyte differentiation; negative regulation of hormone secretion; B cell differentiation; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation

Research Articles on IL11

1. High expression of interleukin-11 correlated with poor prognosis in clear-cell renal cell carcinoma patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL11 antibody

Reference Product	PubMed Publications
IL11RA antibody	>98 publications with IL11 and IL11RA
STAT3 antibody	>97 publications with IL11 and STAT3
IL6ST antibody	>85 publications with IL11 and IL6ST
OSM antibody	>81 publications with IL11 and OSM
CNTF antibody	>72 publications with IL11 and CNTF
IL6 antibody	>38 publications with IL11 and IL6
MPL antibody	>26 publications with IL11 and MPL
LIFR antibody	>23 publications with IL11 and LIFR
IL13RA1 antibody	>1 publications with IL11 and IL13RA1

Pathways associated with anti-IL11 antibody

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Integrated Pancreatic Cancer Pathway antibodies	Integrated Pancreatic Cancer Pathway Diagram
Interleukin-11 Signaling Pathway antibodies	Interleukin-11 Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Rheumatoid Arthritis Pathway antibodies	Rheumatoid Arthritis Pathway Diagram
Rheumatoid Arthritis Pathway antibodies	Rheumatoid Arthritis Pathway Diagram

Diseases associated with anti-IL11 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>173 publications with IL11 and Inflammation
Necrosis Antibodies	>157 publications with IL11 and Necrosis
Disease Models, Animal Antibodies	>90 publications with IL11 and Disease Models, Animal
Lung Diseases Antibodies	>63 publications with IL11 and Lung Diseases
Breast Neoplasms Antibodies	>60 publications with IL11 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>53 publications with IL11 and Cardiovascular Diseases
Liver Diseases Antibodies	>40 publications with IL11 and Liver Diseases
Anemia Antibodies	>37 publications with IL11 and Anemia
Hemorrhage Antibodies	>35 publications with IL11 and Hemorrhage
Fibrosis Antibodies	>31 publications with IL11 and Fibrosis

Organs/Tissues associated with anti-IL11 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>68 publications with IL11 and Intestine
Connective Tissue Antibodies	>57 publications with IL11 and Connective Tissue
Vascular Antibodies	>55 publications with IL11 and Vascular
Brain Antibodies	>49 publications with IL11 and Brain
Embryonic Tissue Antibodies	>45 publications with IL11 and Embryonic Tissue
Kidney Antibodies	>37 publications with IL11 and Kidney
Skin Antibodies	>32 publications with IL11 and Skin
Stomach Antibodies	>27 publications with IL11 and Stomach
Prostate Antibodies	>16 publications with IL11 and Prostate
Pancreas Antibodies	>8 publications with IL11 and Pancreas