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IL22 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9146477

This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL22, Polyclonal Antibody
Full Product Name
IL22 Rabbit pAb
Product Gene Name
anti-IL22 antibody
Product Synonym Names
MXRA2; CH-ILKBP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Ship: Ice Pack
Molecular Weight
372
OMIM
608120
3D Structure
ModBase 3D Structure for Q9NVD7
Positive Samples
MCF7, HT-29, HeLa, NIH/3T3, C6
Research Area
Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Extracellular Matrix
Immunogen
Recombinant protein of human IL22.

Product Categories/Family for anti-IL22 antibody

Polyclonal Antibodies
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IL22 antibody
Western Blot (WB)
Application Notes for anti-IL22 antibody
WB: 1:1000-1:5000

Western Blot (WB) of anti-IL22 antibody

Western blot analysis of various lysates, using IL22 Rabbit pAb (MBS9146477) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Rabbit Anti-IL22 Polyclonal Antibody – Cat# MBS9146477

Other Notes

Small volumes of anti-IL22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL22 purchase

MBS9146477 is an antibody targeting IL22. Also known as IL22 Rabbit pAb. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL22. It may not necessarily be applicable to this product.

NCBI GI #
20139236
NCBI GeneID
55742
NCBI Accession #
Q9NVD7.1
UniProt Primary Accession #
Q9NVD7
UniProt Secondary Accession #
Q96C85; Q9HA48
UniProt Related Accession #
Q9NVD7
NCBI Official Full Name
Alpha-parvin
NCBI Official Synonym Full Names
parvin, alpha
NCBI Official Symbol
PARVA
NCBI Official Synonym Symbols
MXRA2; CH-ILKBP
UniProt Protein Name
Alpha-parvin
UniProt Synonym Protein Names
Actopaxin; CH-ILKBP; Calponin-like integrin-linked kinase-binding protein; Matrix-remodeling-associated protein 2
Protein Family
Interleukin
UniProt Gene Name
PARVA
UniProt Synonym Gene Names
MXRA2
UniProt Entry Name
PARVA_HUMAN
NCBI Protein Information
alpha-parvin; actopaxin; matrix-remodeling-associated protein 2; calponin-like integrin-linked kinase-binding protein

UniProt Comments for IL22

PARVA: Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis. Interacts with TGFB1I1. Interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. Interacts with ARHGAP31. Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. Belongs to the parvin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 11p15.3

Cellular Component: focal adhesion; lamellipodium; cytoplasm; plasma membrane; nucleus; Z disc; cytosol; actin cytoskeleton

Molecular Function: protein binding; actin binding

Biological Process: heterotypic cell-cell adhesion; regulation of cell shape; actin cytoskeleton reorganization; establishment and/or maintenance of cell polarity; sprouting angiogenesis
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Research Articles on IL22

1. alpha-Parvin, a pseudopodial constituent, was found to promote migration of breast cancer cells and to be expressed exclusively by Invasive lobular carcinoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL22 antibody

 Reference Product  PubMed Publications
 ILK antibody  >41 publications with IL22 and ILK
 LIMS2 antibody  >2 publications with IL22 and LIMS2
 AKT1 antibody  >2 publications with IL22 and AKT1
 PXN antibody  >2 publications with IL22 and PXN
 TESK1 antibody  >1 publications with IL22 and TESK1

Pathways associated with anti-IL22 antibody

 Products by Pathway  Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-extracellular Matrix Interactions Pathway antibodies  Cell-extracellular Matrix Interactions Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Localization Of The PINCH-ILK-PARVIN Complex To Focal Adhesions Pathway antibodies  Localization Of The PINCH-ILK-PARVIN Complex To Focal Adhesions Pathway Diagram
 Regulation Of Cytoskeletal Remodeling And Cell Spreading By IPP Complex Components Pathway antibodies  Regulation Of Cytoskeletal Remodeling And Cell Spreading By IPP Complex Components Pathway Diagram

Diseases associated with anti-IL22 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >29 publications with IL22 and Cardiovascular Diseases
 Inflammation Antibodies  >19 publications with IL22 and Inflammation
 Lung Diseases Antibodies  >16 publications with IL22 and Lung Diseases
 Disease Models, Animal Antibodies  >13 publications with IL22 and Disease Models, Animal
 Nervous System Diseases Antibodies  >13 publications with IL22 and Nervous System Diseases
 Necrosis Antibodies  >13 publications with IL22 and Necrosis
 Anemia Antibodies  >12 publications with IL22 and Anemia
 Liver Diseases Antibodies  >10 publications with IL22 and Liver Diseases
 Edema Antibodies  >9 publications with IL22 and Edema
 Weight Gain Antibodies  >7 publications with IL22 and Weight Gain

Organs/Tissues associated with anti-IL22 antibody

 Organ/Tissue Name  Pubmed Publications
 Salivary Gland Antibodies  >75 publications with IL22 and Salivary Gland
 Mouth Antibodies  >63 publications with IL22 and Mouth
 Vascular Antibodies  >38 publications with IL22 and Vascular
 Intestine Antibodies  >28 publications with IL22 and Intestine
 Liver Antibodies  >26 publications with IL22 and Liver
 Brain Antibodies  >26 publications with IL22 and Brain
 Muscle Antibodies  >24 publications with IL22 and Muscle
 Bone Antibodies  >20 publications with IL22 and Bone
 Kidney Antibodies  >17 publications with IL22 and Kidney
 Skin Antibodies  >16 publications with IL22 and Skin
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