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L-PLASTIN Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS462234

L-plastin is a protein normally found in leukocytes (white blood cells) only. In these cells L-plastin regulates cell movement by interacting with actins, a major cellular protein that directly controls cell movement. Normal breast epithelial cells do not… More details

$355 / 0.1 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
L-Plastin, Polyclonal Antibody
Full Product Name
Rabbit anti L-Plastin/LCP1 Polyclonal antibody
Product Gene Name
anti-L-Plastin antibody
Product Synonym Names
Rabbit anti-L-Plastin; Lymphocyte cytosolic protein-1 (LCP1); L-plastin; LC64P; CP64; Plastin 2 (PLS2)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Form/Format
This affinity purified antibody is supplied in sterile phosphatebuffered saline (pH7.2) containing antibody stabilizer
Purity/Purification
The Rabbit IgG is purified by Epitope Affinity Purification.
Concentration
Size: 100 ug/200 ul (lot specific)
Specificity
This antibody recognizes ~70 kDa of L-plastin protein. It also reacts with human, mouse and rat. The other species are not tested.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
~70 kDa
Antigen Preparation
A synthetic peptide corresponding to the C-terminus of human L-plastin protein. This sequence is identical to rat, mouse and human origins
Positive Control
HL60 cells
Cellular Location
Cytoplasmic
Applications Tested/Suitable for anti-L-Plastin antibody
ELISA, Western Blot
Application Notes for anti-L-Plastin antibody
Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 0.5-2 ug/ml

Testing Data of anti-L-Plastin antibody

Rabbit Anti-L-PLASTIN Polyclonal Antibody – Cat# MBS462234

Product References and Citations for anti-L-Plastin antibody

Foran,E., et al, The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells. Int. J. Cancer 118 (8), 2098-2104 (2006)

Other Notes

Small volumes of anti-L-Plastin antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for L-Plastin purchase

MBS462234 is an antibody targeting L-Plastin. Also known as Rabbit anti L-Plastin/LCP1 Polyclonal antibody. Reactive in Human, Rat, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for L-Plastin. It may not necessarily be applicable to this product.

NCBI GI #
187222
NCBI Official Full Name
L-plastin
Protein Family
Plastin

UniProt Comments for L-Plastin

L-plastin: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Monomer. Interacts with AIF1. Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

Protein type: Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 13q14.3

Cellular Component: ruffle; extracellular space; focal adhesion; cytoplasm; actin filament bundle; plasma membrane; stress fiber; actin filament; cytosol; actin cytoskeleton; phagocytic cup; filopodium

Molecular Function: actin filament binding; identical protein binding; calcium ion binding; actin binding

Biological Process: actin filament bundle formation; organ regeneration; cell migration; regulation of intracellular protein transport; T cell activation during immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-L-Plastin antibody

 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with L-Plastin and FLNA

Pathways associated with anti-L-Plastin antibody

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram

Organs/Tissues associated with anti-L-Plastin antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with L-Plastin and Bone
 Connective Tissue Antibodies  >4 publications with L-Plastin and Connective Tissue
 Heart Antibodies  >3 publications with L-Plastin and Heart
 Muscle Antibodies  >3 publications with L-Plastin and Muscle
 Brain Antibodies  >3 publications with L-Plastin and Brain
 Vascular Antibodies  >2 publications with L-Plastin and Vascular
 Embryonic Tissue Antibodies  >2 publications with L-Plastin and Embryonic Tissue
 Ear Antibodies  >1 publications with L-Plastin and Ear
 Kidney Antibodies  >1 publications with L-Plastin and Kidney
 Umbilical Cord Antibodies  >1 publications with L-Plastin and Umbilical Cord
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