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LAX1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7600943

MBS7600943 is an antibody targeting LAX1. Also known as LAX1 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LAX1, Polyclonal Antibody
Full Product Name
LAX1 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
42,491 Da
Immunogen
Lymphocyte transmembrane adaptor 1
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-LAX1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-LAX1 antibody

Immunohistochemistry of paraffin-embedded human spleen using MBS7600943 (LAX1 antibody) at dilution of 1:100
Rabbit Anti-LAX1 Polyclonal Antibody – Cat# MBS7600943

Western Blot (WB) of anti-LAX1 antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS7600943 (LAX1 antibody) at dilution of 1:1500
Rabbit Anti-LAX1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS7600943

Other Notes

Small volumes of anti-LAX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LAX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lymphocyte transmembrane adapter 1 isoform c
NCBI Official Synonym Full Names
lymphocyte transmembrane adaptor 1
NCBI Official Symbol
LAX1
NCBI Official Synonym Symbols
LAX
UniProt Protein Name
Lymphocyte transmembrane adapter 1
UniProt Synonym Protein Names
Linker for activation of X cells; Membrane-associated adapter protein LAX
UniProt Gene Name
LAX1
UniProt Synonym Gene Names
LAX
UniProt Entry Name
LAX1_HUMAN
NCBI Protein Information
lymphocyte transmembrane adapter 1

UniProt Comments for LAX1

LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: cytoplasm; Golgi apparatus; integral to membrane; lipid raft; membrane; plasma membrane

Molecular Function: protein binding; protein kinase binding; SH2 domain binding

Biological Process: adaptive immune response; antigen receptor-mediated signaling pathway; B cell activation; immune response; immunoglobulin secretion; inactivation of MAPK activity; negative regulation of T cell activation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-LAX1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with LAX1 and Blood
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