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LFG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9408304

Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently… More details

$595 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LFG, Polyclonal Antibody
Full Product Name
LFG Antibody
Product Gene Name
anti-LFG antibody
Product Synonym Names
Lifeguard, Fas apoptotic inhibitory molecule2, FAIM2, NMP35
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Purity/Purification
Affinity chromatography purified via peptide column
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
30,448 Da
OMIM
604306
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide from near the amino terminus of human LFG.
Target Name
LFG

Product Categories/Family for anti-LFG antibody

Total protein Ab
Applications Tested/Suitable for anti-LFG antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-LFG antibody

Western blot analysis of LFG in EL4 cell lysate with LFG antibody at (A) 0.5 and (B) 1 ug/mL.
Rabbit Anti-LFG Polyclonal Antibody – Cat# MBS9408304

Immunohistochemistry (IHC) of anti-LFG antibody

Immunohistochemistry of LFG in mouse brain tissue with LFG antibody at 5 ug/mL.
Rabbit Anti-LFG Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9408304

Other Notes

Small volumes of anti-LFG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LFG purchase

MBS9408304 is an antibody targeting LFG. Also known as LFG Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LFG. It may not necessarily be applicable to this product.

NCBI GI #
6273281
NCBI Accession #
AAF06327
UniProt Secondary Accession #
Q9UJY9; Q9Y2F7; A8K1W6; B3KR08
NCBI Official Full Name
lifeguard
UniProt Protein Name
Protein lifeguard 2
UniProt Synonym Protein Names
Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
UniProt Gene Name
FAIM2
UniProt Synonym Gene Names
KIAA0950; LFG; LFG2; NMP35; TMBIM2
UniProt Entry Name
LFG2_HUMAN

UniProt Comments for LFG

FAIM2: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. Belongs to the BI1 family. LFG subfamily.

Protein type: Membrane protein, integral; Apoptosis; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: postsynaptic membrane; integral to membrane; cell junction; lipid raft

Biological Process: cerebellar granular layer development; apoptosis; regulation of neuron apoptosis; cerebellar Purkinje cell differentiation; cerebellar Purkinje cell layer development; cerebellum development; negative regulation of neuron apoptosis; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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