Rabbit Anti-MMP16 Polyclonal Antibody – Cat# MBS8566475

MMP16 Antibody – Rabbit Polyclonal

Name: MMP16 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8566475
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8566475

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as… More details

$380 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MMP16, Polyclonal Antibody

Full Product Name

MMP16 Polyclonal Antibody

Product Gene Name

anti-MMP16 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.

Purity/Purification

Affinity Purification

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

Molecular Weight

52kDa; 69kDa

OMIM

602262

3D Structure

ModBase 3D Structure for P51512

Immunogen

Recombinant protein of human MMP16 (NP_005932.2).

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-MMP16 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes for anti-MMP16 antibody

WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200

Other Notes

Small volumes of anti-MMP16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MMP16 purchase

MBS8566475 is an antibody targeting MMP16. Also known as MMP16 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MMP16. It may not necessarily be applicable to this product.

NCBI GI #

13027802

NCBI GeneID

4325

NCBI Accession #

NP_005932.2

UniProt Primary Accession #

P51512

UniProt Related Accession #

P51512

GenBank Nucleotide #

NP_005932.2

NCBI Official Full Name

matrix metalloproteinase-16

NCBI Official Synonym Full Names

matrix metallopeptidase 16

NCBI Official Symbol

MMP16

NCBI Official Synonym Symbols

MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP

UniProt Protein Name

Matrix metalloproteinase-16

UniProt Synonym Protein Names

MMP-X2; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase

Protein Family

Matrix metalloproteinase

UniProt Gene Name

MMP16

UniProt Synonym Gene Names

MMPX2; MMP-16; MT-MMP 3; MTMMP3; MT3-MMP; MT3MMP

UniProt Entry Name

MMP16_HUMAN

NCBI Protein Information

matrix metalloproteinase-16

UniProt Comments for MMP16

MMP16: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. Belongs to the peptidase M10A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Membrane protein, integral; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: proteinaceous extracellular matrix; cell surface; integral to plasma membrane; Golgi lumen; plasma membrane

Molecular Function: zinc ion binding; metalloendopeptidase activity; enzyme activator activity; calcium ion binding

Biological Process: positive regulation of catalytic activity; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; embryonic cranial skeleton morphogenesis; proteolysis; endochondral ossification

Research Articles on MMP16

1. Overexpression of MMP2 and MMP16 in endometrial cancerous tissues corresponded to down-regulation of miR-377, miR-382 and miR-410, while decreased expression of TIMP2 was associated with miR-200b up-regulation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MMP16 antibody

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Matrix Metalloproteinases Pathway antibodies	Matrix Metalloproteinases Pathway Diagram

Diseases associated with anti-MMP16 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>24 publications with MMP16 and Neoplasms
Breast Neoplasms Antibodies	>5 publications with MMP16 and Breast Neoplasms
Fibrosis Antibodies	>3 publications with MMP16 and Fibrosis
Ovarian Neoplasms Antibodies	>2 publications with MMP16 and Ovarian Neoplasms
Nervous System Diseases Antibodies	>2 publications with MMP16 and Nervous System Diseases
Lung Diseases Antibodies	>2 publications with MMP16 and Lung Diseases
Necrosis Antibodies	>2 publications with MMP16 and Necrosis
Prostatic Neoplasms Antibodies	>1 publications with MMP16 and Prostatic Neoplasms
Glioblastoma Antibodies	>1 publications with MMP16 and Glioblastoma
Kidney Diseases Antibodies	>1 publications with MMP16 and Kidney Diseases

Organs/Tissues associated with anti-MMP16 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>8 publications with MMP16 and Vascular
Lung Antibodies	>5 publications with MMP16 and Lung
Brain Antibodies	>5 publications with MMP16 and Brain
Kidney Antibodies	>4 publications with MMP16 and Kidney
Muscle Antibodies	>4 publications with MMP16 and Muscle
Prostate Antibodies	>3 publications with MMP16 and Prostate
Skin Antibodies	>3 publications with MMP16 and Skin
Placenta Antibodies	>3 publications with MMP16 and Placenta
Embryonic Tissue Antibodies	>3 publications with MMP16 and Embryonic Tissue
Connective Tissue Antibodies	>3 publications with MMP16 and Connective Tissue