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MPHOSPH8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9419449

MBS9419449 is an antibody targeting MPHOSPH8. Also known as MPHOSPH8 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$260 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MPHOSPH8, Polyclonal Antibody
Full Product Name
MPHOSPH8 Antibody
Product Gene Name
Product Synonym Names
MPP8
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Specificity
MPHOSPH8 Antibody detects endogenous levels of total MPHOSPH8
Preparation and Storage
Store at -20 degree C
Molecular Weight
97,637 Da
OMIM
AK056785 mRNA
3D Structure
ModBase 3D Structure for Q99549
Immunogen
A synthesized peptide derived from human MPHOSPH8
Immunogen Type
Peptide

Product Categories/Family for anti-MPHOSPH8 antibody

Applications Tested/Suitable for anti-MPHOSPH8 antibody
Western Blot (WB)
Application Notes for anti-MPHOSPH8 antibody
Western Blot: 1:1000-3000

Western Blot (WB) of anti-MPHOSPH8 antibody

Western blot analysis MPHOSPH8 using COLO205 whole cell lysates
Rabbit Anti-MPHOSPH8 Polyclonal Antibody – Cat# MBS9419449

Other Notes

Small volumes of anti-MPHOSPH8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MPHOSPH8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
M-phase phosphoprotein 8
NCBI Official Synonym Full Names
M-phase phosphoprotein 8
NCBI Official Symbol
MPHOSPH8
NCBI Official Synonym Symbols
TWA3; mpp8; HSMPP8
UniProt Protein Name
M-phase phosphoprotein 8
UniProt Synonym Protein Names
Two hybrid-associated protein 3 with RanBPM
UniProt Gene Name
MPHOSPH8
UniProt Synonym Gene Names
Twa3
UniProt Entry Name
MPP8_HUMAN
NCBI Protein Information
M-phase phosphoprotein 8

UniProt Comments for MPHOSPH8

MPHOSPH8: Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 13q12.11

Cellular Component: cytoplasm; nuclear heterochromatin; nucleolus; nucleus; plasma membrane; ubiquitin ligase complex

Molecular Function: methylated histone residue binding; protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity

Biological Process: negative regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MPHOSPH8 antibody

 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >1 publications with MPHOSPH8 and Thyroid
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