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MTP18 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8307332

MBS8307332 is an antibody targeting MTP18. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to MTP18 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTP18, Polyclonal Antibody
Full Product Name
Anti-MTP18 Antibody
Product Gene Name
Product Synonym Gene Name
MTFP1
Product Synonym Names
MTP18; Mitochondrial fission process protein 1; Mitochondrial 18 kDa protein; MTP18
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Specificity
Recognizes endogenous levels of MTP18 protein.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
166
OMIM
610235
3D Structure
ModBase 3D Structure for Q9UDX5
Immunogen
Recombinant fusion protein of human MTP18. The exact sequence is proprietary.
Applications Tested/Suitable for anti-MTP18 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MTP18 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-MTP18 antibody

Western blot analysis of MTP18 expression in mouse liver (A), rat heart (B) whole cell lysates.
Rabbit Anti-MTP18 Polyclonal Antibody – Cat# MBS8307332

Immunohistochemistry (IHC) of anti-MTP18 antibody

Immunohistochemical analysis of MTP18 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-MTP18 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS8307332

Other Notes

Small volumes of anti-MTP18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MTP18. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Mitochondrial fission process protein 1
NCBI Official Synonym Full Names
mitochondrial fission process 1
NCBI Official Symbol
MTFP1
NCBI Official Synonym Symbols
MTP18; HSPC242
UniProt Protein Name
Mitochondrial fission process protein 1
UniProt Synonym Protein Names
Mitochondrial 18 kDa protein; MTP18
UniProt Gene Name
MTFP1
UniProt Synonym Gene Names
MTP18; MTP18
UniProt Entry Name
MTFP1_HUMAN
NCBI Protein Information
mitochondrial fission process protein 1; mitochondrial 18 kDa protein; mitochondrial protein 18 kDa; mitochondrial fission protein MTP18

NCBI Summary for MTP18

MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase (see PIK3CA, MIM 171834) signaling pathway that plays a role in cell viability and mitochondrial dynamics (Tondera et al., 2004 [PubMed 15155745]).[supplied by OMIM, Mar 2008]

UniProt Comments for MTP18

MTP18: Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis. Belongs to the MTFP1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial

Chromosomal Location of Human Ortholog: 22q

Cellular Component: mitochondrial inner membrane; integral to membrane

Biological Process: mitochondrial fission; apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MTP18 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with MTP18 and Muscle
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