Rabbit Anti-OBFC2A Polyclonal Antibody – Cat# MBS9521736

OBFC2A Antibody – Rabbit Polyclonal

Name: OBFC2A Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9521736
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9521736

MBS9521736 is an antibody targeting OBFC2A. Also known as OBFC2A Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$265 / 0.04 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

OBFC2A, Polyclonal Antibody

Full Product Name

OBFC2A Antibody

Product Gene Name

anti-OBFC2A antibody

Product Synonym Names

SOSS complex subunit B2 (Nucleic acid-binding protein 1)(Oligonucleotide/oligosaccharide-binding fold-containing protein 2A)(Sensor of single-strand DNA complex subunit B2)(Sensor of ssDNA subunit B2)(SOSS-B2)(Single-stranded DNA-binding protein 2)(hSSB2)

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purity/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1mg/ml (lot specific)

Specificity

This antibody detects endogenous levels of OBFC2A at Human, Mouse,Rat

Preparation and Storage

Store at -20 degree C/1 year

Molecular Weight

14,677 Da

OMIM

612103

3D Structure

ModBase 3D Structure for Q96AH0

Immunogen

Synthesized peptide derived from human OBFC2A

Modification

Unmodified/Total

Product Categories/Family for anti-OBFC2A antibody

Primary Antibodies

Applications Tested/Suitable for anti-OBFC2A antibody

Western Blot (WB)

Application Notes for anti-OBFC2A antibody

WB: 1:500-2000

Other Notes

Small volumes of anti-OBFC2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OBFC2A. It may not necessarily be applicable to this product.

NCBI GI #

72534722

NCBI GeneID

64859

NCBI Accession #

NP_001026886.1

UniProt Primary Accession #

Q96AH0

UniProt Secondary Accession #

Q658Y8; Q9H5X6

UniProt Related Accession #

Q96AH0

GenBank Nucleotide #

NM_001031716.2

NCBI Official Full Name

SOSS complex subunit B2 isoform 1

NCBI Official Synonym Full Names

nucleic acid binding protein 1

NCBI Official Symbol

NABP1

NCBI Official Synonym Symbols

SSB2; OBFC2A; SOSS-B2

UniProt Protein Name

SOSS complex subunit B2

UniProt Synonym Protein Names

Nucleic acid-binding protein 1; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A; Sensor of single-strand DNA complex subunit B2; Sensor of ssDNA subunit B2; SOSS-B2; Single-stranded DNA-binding protein 2; hSSB2

UniProt Gene Name

NABP1

UniProt Synonym Gene Names

OBFC2A; SSB2; SOSS-B2; hSSB2

UniProt Entry Name

SOSB2_HUMAN

NCBI Protein Information

SOSS complex subunit B2; nucleic acid-binding protein 1; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; sensor of single-strand DNA complex subunit B2; sensor of ssDNA subuni

NCBI Summary for OBFC2A

Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2A, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008]

UniProt Comments for OBFC2A

OBFC2A: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. Belongs to the SOSS-B family. SOSS-B2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; DNA repair, damage; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: RNA binding; single-stranded DNA binding

Biological Process: mitotic cell cycle checkpoint; response to ionizing radiation; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination

Research Articles on OBFC2A

1. hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OBFC2A antibody

Reference Product	PubMed Publications
INTS3 antibody	>1 publications with OBFC2A and INTS3

Organs/Tissues associated with anti-OBFC2A antibody

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>1 publications with OBFC2A and Thyroid
Thymus Antibodies	>1 publications with OBFC2A and Thymus