• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

p15 INK Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9504689

MBS9504689 is an antibody targeting p15 INK. Also known as p15 INK Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$300 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
p15 INK, Polyclonal Antibody
Full Product Name
p15 INK Antibody
Product Gene Name
Product Synonym Gene Name
CDKN2B
Product Synonym Names
CDKN2B; CDN2B; Cyclin-dependent kinase 4 inhibitor B; MTS2; Multiple tumor suppressor 2; p14-INK4b
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
1 mg/ml (lot specific)
Specificity
p15 INK Antibody detects endogenous levels of total p15 INK protein.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Molecular Weight
14 kDa
OMIM
U17075 mRNA
3D Structure
ModBase 3D Structure for P42772
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human p15 INK.
Immunogen Range
89-138
Applications Tested/Suitable for anti-p15 INK antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-p15 INK antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000

Immunofluorescence (IF) of anti-p15 INK antibody

Immunofluorescence analysis of HeLa cells, using p15 INK Antibody. The picture on the right is blocked with the synthesized peptide.
Rabbit Anti-p15 INK Polyclonal Antibody – Cat# MBS9504689

Immunohistochemistry (IHC) of anti-p15 INK antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using p15 INK Antibody. The picture on the right is blocked with the synthesized peptide.
Rabbit Anti-p15 INK Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9504689

Western Blot (WB) of anti-p15 INK antibody

Western blot analysis of lysates from HeLa cells, using p15 INK Antibody. The lane on the right is blocked with the synthesized peptide.
Rabbit Anti-p15 INK Polyclonal Antibody, Western Blot (WB) – Cat# MBS9504689

Other Notes

Small volumes of anti-p15 INK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for p15 INK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase 4 inhibitor B isoform 1
NCBI Official Synonym Full Names
cyclin dependent kinase inhibitor 2B
NCBI Official Symbol
CDKN2B
NCBI Official Synonym Symbols
P15; MTS2; TP15; CDK4I; INK4B; p15INK4b
UniProt Protein Name
Cyclin-dependent kinase 4 inhibitor B
UniProt Synonym Protein Names
Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B
UniProt Gene Name
CDKN2B
UniProt Synonym Gene Names
MTS2; MTS-2; p15INK4B
NCBI Protein Information
cyclin-dependent kinase 4 inhibitor B

NCBI Summary for p15 INK

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for p15 INK

Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-p15 INK antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000