Rabbit Anti-P4HA2 Polyclonal Antibody – Cat# MBS9433669

Western blot analysis of extracts of various cell lines, using P4HA2 antibody.

P4HA2 Antibody – Rabbit Polyclonal

Name: P4HA2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9433669
Price: 320 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9433669

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of… More details

$320 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

P4HA2, Polyclonal Antibody

Full Product Name

P4HA2 Polyclonal Antibody

Product Gene Name

anti-P4HA2 antibody

Product Synonym Names

P4HA2; MYP25; prolyl 4-hydroxylase subunit alpha-2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

PBS with 50% glycerol, pH7.4

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

Molecular Weight

65kDa

OMIM

600608

3D Structure

ModBase 3D Structure for O15460

Immunogen

Recombinant fusion protein of human P4HA2 (NP_001136070.1).

Conjugation

Unconjugated

Product Categories/Family for anti-P4HA2 antibody

Total protein Ab

Applications Tested/Suitable for anti-P4HA2 antibody

Western Blot (WB)

Application Notes for anti-P4HA2 antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-P4HA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P4HA2 purchase

MBS9433669 is an antibody targeting P4HA2. Also known as P4HA2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for P4HA2. It may not necessarily be applicable to this product.

NCBI GI #

217272861

NCBI GeneID

8974

NCBI Accession #

NP_001136070.1

UniProt Primary Accession #

O15460

UniProt Related Accession #

O15460

GenBank Nucleotide #

NP_001136070.1

NCBI Official Full Name

prolyl 4-hydroxylase subunit alpha-2 isoform 2

NCBI Official Synonym Full Names

prolyl 4-hydroxylase subunit alpha 2

NCBI Official Symbol

P4HA2

NCBI Official Synonym Symbols

MYP25

UniProt Protein Name

Prolyl 4-hydroxylase subunit alpha-2

UniProt Synonym Protein Names

Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2

Protein Family

Prolyl 4-hydroxylase

UniProt Gene Name

P4HA2

UniProt Synonym Gene Names

4-PH alpha-2

UniProt Entry Name

P4HA2_HUMAN

NCBI Protein Information

prolyl 4-hydroxylase subunit alpha-2

UniProt Comments for P4HA2

P4HA2: Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Belongs to the P4HA family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.11.2; Oxidoreductase; Secreted, signal peptide; Amino Acid Metabolism - arginine and proline; Secreted

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum lumen; endoplasmic reticulum; cytoplasm; nucleus

Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; procollagen-proline 4-dioxygenase activity; electron carrier activity; L-ascorbic acid binding; iron ion binding

Biological Process: peptidyl-proline hydroxylation to 4-hydroxy-L-proline

Research Articles on P4HA2

1. The data show that a low P4HA2 and high PRTN3 expression correlates with poor survival in patients with pancreatic cancer, indicating the involvement of collagen deposition in the restraint of the tumor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.