PDZD2 Antibody – Rabbit Polyclonal

Description: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.
Subunit Structure: Interacts with SCN10A, CTNND2 and PKP4.
Post-translational Modifications: A secreted form is produced by caspase-mediated proteolytic cleavage.

Small volumes of anti-PDZD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9600253 is an antibody targeting PDZD2. Also known as PDZD2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.