Rabbit Anti-PGCF Polyclonal Antibody – Cat# MBS543741

PGCF Antibody – Rabbit Polyclonal

Name: PGCF Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS543741
Price: 610 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS543741

BIOTIN-Conjugated Guanylyl Cyclase F AntibodyProbably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. More details

$610 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PGCF, Polyclonal Antibody

Full Product Name

PGCF Antibody BIOTIN-Conjugated

Product Gene Name

anti-PGCF antibody

Product Synonym Names

Particulate Guanylate Cyclase F antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

BIOTIN-Conjugated

Concentration

0.75-1.20 ug/ul in antibody stabilization buffer (lot specific)

Preparation and Storage

-20 degree C for long term storage

Matching Pairs

Antibody: PGCF (MBS543741)
Positive Control: PGCF (MBS543119)

Antibody/Peptide Pairs

PGCF peptide (MBS544258) is used for blocking the activity of PGCF antibody (MBS543741)

Molecular Weight

124,411 Da

3D Structure

ModBase 3D Structure for P51842

Immunogen

Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein.

Expression

Expressed only in the eye.

Molecular Function

Lyase

Structure

Belongs to the adenylyl cyclase-class-4/guanylyl cyclase family. Contains 1 guanylate cyclase domain. Contains 1 protein kinase domain.

Subcellular Location

Membrane; Single-pass type I membrane protein

Applications Tested/Suitable for anti-PGCF antibody

Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-PGCF antibody

Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500

Other Notes

Small volumes of anti-PGCF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGCF purchase

MBS543741 is an antibody targeting PGCF. Also known as PGCF Antibody BIOTIN-Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PGCF. It may not necessarily be applicable to this product.

NCBI GI #

780356

NCBI GeneID

79222

NCBI Accession #

L36029.1

UniProt Primary Accession #

P51842

UniProt Related Accession #

P51840

NCBI Official Full Name

Rattus norvegicus guanylyl cyclase (GC-E), complete cds

NCBI Official Synonym Full Names

guanylate cyclase 2E

NCBI Official Symbol

Gucy2e

UniProt Protein Name

Retinal guanylyl cyclase 2

UniProt Synonym Protein Names

Guanylate cyclase 2F, retinal; Guanylate cyclase F; GC-F; Rod outer segment membrane guanylate cyclase 2; ROS-GC2

UniProt Gene Name

Gucy2f

UniProt Synonym Gene Names

Guc2f; RETGC-2; GC-F; ROS-GC2

UniProt Entry Name

GUC2F_RAT

NCBI Protein Information

guanylyl cyclase GC-E

NCBI Summary for PGCF

an orphan membrane guanylyl cyclase [RGD, Feb 2006]

UniProt Comments for PGCF

GUCY2F: Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Nucleotide Metabolism - purine; Membrane protein, integral; Guanylyl cyclase; Receptor, misc.; Kinase, protein; EC 4.6.1.2; Protein kinase, RGC; Protein kinase, dual-specificity (receptor); Lyase; RGC group; RGC family

Cellular Component: guanylate cyclase complex, soluble; integral to membrane; membrane; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; GTP binding; guanylate cyclase activity; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase activity

Biological Process: cGMP biosynthetic process; detection of light stimulus involved in visual perception; protein amino acid phosphorylation; receptor guanylyl cyclase signaling pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PGCF antibody

Products by Pathway	Pathway Diagram
Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway antibodies	Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Olfactory Transduction Pathway antibodies	Olfactory Transduction Pathway Diagram
Olfactory Transduction Pathway antibodies	Olfactory Transduction Pathway Diagram
Phototransduction Pathway antibodies	Phototransduction Pathway Diagram
Phototransduction Pathway antibodies	Phototransduction Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
The Phototransduction Cascade Pathway antibodies	The Phototransduction Cascade Pathway Diagram

Diseases associated with anti-PGCF antibody

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>3 publications with PGCF and Disease Models, Animal
Nerve Degeneration Antibodies	>1 publications with PGCF and Nerve Degeneration
Congenital Abnormalities Antibodies	>1 publications with PGCF and Congenital Abnormalities