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PRMT3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9129649
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This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
PRMT3, Polyclonal Antibody
Full Product Name
PRMT3 Polyclonal Antibody
Product Gene Name
anti-PRMT3 antibody
Product Synonym Names
HRMT1L3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
Calculated MW: 60kDa
Molecular Weight: 531
OMIM
603190
3D Structure
ModBase 3D Structure for O60678
Immunogen
Recombinant protein of human PRMT3

Product Categories/Family for anti-PRMT3 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PRMT3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PRMT3 antibody
WB: 1:200 - 1:2000, IHC: 1:20 - 1:200

Western Blot (WB) of anti-PRMT3 antibody

Western blot analysis of extracts of mouse brain, using PRMT3 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-PRMT3 Polyclonal Antibody – Cat# MBS9129649

Other Notes

Small volumes of anti-PRMT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRMT3 purchase

MBS9129649 is an antibody targeting PRMT3. Also known as PRMT3 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRMT3. It may not necessarily be applicable to this product.

NCBI GI #
44771198
NCBI GeneID
10196
NCBI Accession #
NP_005779.1
UniProt Primary Accession #
O60678
UniProt Secondary Accession #
B4DUC7
UniProt Related Accession #
O60678
GenBank Nucleotide #
NM_005788.3
NCBI Official Full Name
protein arginine N-methyltransferase 3 isoform 1
NCBI Official Synonym Full Names
protein arginine methyltransferase 3
NCBI Official Symbol
PRMT3
NCBI Official Synonym Symbols
HRMT1L3
UniProt Protein Name
Protein arginine N-methyltransferase 3
UniProt Synonym Protein Names
Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
Protein Family
Probable protein arginine N-methyltransferase
UniProt Gene Name
PRMT3
UniProt Synonym Gene Names
HRMT1L3
UniProt Entry Name
ANM3_HUMAN
NCBI Protein Information
protein arginine N-methyltransferase 3

UniProt Comments for PRMT3

PRMT3: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. Belongs to the protein arginine N-methyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.1.1.-; Methyltransferase; Methyltransferase, protein arginine; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: cytoplasm; cytosol; ribosome

Molecular Function: histone-arginine N-methyltransferase activity; metal ion binding; methyltransferase activity; protein binding; protein-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity

Biological Process: negative regulation of protein ubiquitination; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; peptidyl-arginine N-methylation; regulation of transcription, DNA-dependent
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Research Articles on PRMT3

1. PRMT3 translocation by palmitic acid is coupled to the binding of LXRalpha, which is responsible for the onset of fatty liver.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-PRMT3 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with PRMT3 and Breast Neoplasms
 Lung Neoplasms Antibodies  >3 publications with PRMT3 and Lung Neoplasms
 Lung Diseases Antibodies  >3 publications with PRMT3 and Lung Diseases
 Liver Diseases Antibodies  >2 publications with PRMT3 and Liver Diseases
 Death Antibodies  >2 publications with PRMT3 and Death
 Fatty Liver Antibodies  >2 publications with PRMT3 and Fatty Liver
 Hypertension Antibodies  >2 publications with PRMT3 and Hypertension
 Heart Diseases Antibodies  >1 publications with PRMT3 and Heart Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with PRMT3 and Cell Transformation, Neoplastic
 Fibrosis Antibodies  >1 publications with PRMT3 and Fibrosis

Organs/Tissues associated with anti-PRMT3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with PRMT3 and Brain
 Lung Antibodies  >5 publications with PRMT3 and Lung
 Liver Antibodies  >4 publications with PRMT3 and Liver
 Muscle Antibodies  >3 publications with PRMT3 and Muscle
 Blood Antibodies  >3 publications with PRMT3 and Blood
 Vascular Antibodies  >2 publications with PRMT3 and Vascular
 Intestine Antibodies  >2 publications with PRMT3 and Intestine
 Embryonic Tissue Antibodies  >2 publications with PRMT3 and Embryonic Tissue
 Bone Antibodies  >1 publications with PRMT3 and Bone
 Skin Antibodies  >1 publications with PRMT3 and Skin
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