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PYGO1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6270045

MBS6270045 is an antibody targeting Pygo1. Also known as Pygo1 (Pygopus Homolog 1) (AP). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$1040 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pygo1, Polyclonal Antibody
Full Product Name
Pygo1 (Pygopus Homolog 1) (AP)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by affinity chromatography.
Specificity
Recognizes human Pygo1. Species Crossreactivity: mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
45,318 Da
OMIM
606902
3D Structure
ModBase 3D Structure for Q9Y3Y4
Immunogen
Synthetic linear peptide corresponding to human Pygopus Homolog 1 (KLH). Species sequence homology: chimpanzee and rhesus macaque (100%).
Conjugate
AP
Positive Control
Human placenta tissue lysate
Note
Preservative Free

Product Categories/Family for anti-Pygo1 antibody

Applications Tested/Suitable for anti-Pygo1 antibody
Western Blot (WB)
Application Notes for anti-Pygo1 antibody
WB: 0.1ug/ml
Applications are based on unconjugated antibody.

Product References and Citations for anti-Pygo1 antibody

1. Kramps, T., et al. (2002). Cell. 109(1):46-60. 2. Hoffmans, R., et al. (2007). Mech Dev. 124(1):59-67.

Other Notes

Small volumes of anti-Pygo1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Pygo1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pygopus homolog 1
NCBI Official Synonym Full Names
pygopus family PHD finger 1
NCBI Official Symbol
PYGO1
UniProt Protein Name
Pygopus homolog 1
Protein Family
UniProt Gene Name
PYGO1
UniProt Entry Name
PYGO1_HUMAN
NCBI Protein Information
pygopus homolog 1; pygopus-like protein 1

UniProt Comments for Pygo1

Function: Involved in signal transduction through the Wnt pathway.

Subunit structure: Binds to BCL9 via The PHD-type zinc finger motiv, and thereby becomes part of the nuclear beta-catenin/TCF complex. Found in a complex with BCL9L, CDC73, CTNNB1 and PYGO1.

Subcellular location: Nucleus

Probable.

Sequence similarities: Contains 1 PHD-type zinc finger.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-Pygo1 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >1 publications with Pygo1 and Intestine
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