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RAB21 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9407744

This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAB21, Polyclonal Antibody
Full Product Name
RAB21 Antibody
Product Gene Name
anti-RAB21 antibody
Product Synonym Names
KIAA0118; RAB21
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
2.2 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total RAB21 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
24,348 Da
OMIM
612398
3D Structure
ModBase 3D Structure for Q9UL25
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human RAB21, member RAS oncogene family
Target Name
RAB21

Product Categories/Family for anti-RAB21 antibody

Total protein Ab
Applications Tested/Suitable for anti-RAB21 antibody
Immunohistochemistry (IHC)
Application Notes for anti-RAB21 antibody
Immunohistochemistry: 1:25-1:100

Immunohistochemistry (IHC) of anti-RAB21 antibody

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/35.
Rabbit Anti-RAB21 Polyclonal Antibody – Cat# MBS9407744

Other Notes

Small volumes of anti-RAB21 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB21 purchase

MBS9407744 is an antibody targeting RAB21. Also known as RAB21 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB21. It may not necessarily be applicable to this product.

NCBI GI #
7661922
NCBI GeneID
23011
NCBI Accession #
NP_055814.1
UniProt Primary Accession #
Q9UL25
UniProt Secondary Accession #
Q14466; Q569H3
UniProt Related Accession #
Q9UL25
GenBank Nucleotide #
NM_014999.2
NCBI Official Full Name
ras-related protein Rab-21
NCBI Official Synonym Full Names
RAB21, member RAS oncogene family
NCBI Official Symbol
RAB21
UniProt Protein Name
Ras-related protein Rab-21
Protein Family
Ras-related protein
UniProt Gene Name
RAB21
UniProt Synonym Gene Names
KIAA0118
UniProt Entry Name
RAB21_HUMAN
NCBI Protein Information
ras-related protein Rab-21

UniProt Comments for RAB21

RAB21: Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Belongs to the small GTPase superfamily. Rab family.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric, Rab; G protein, monomeric

Chromosomal Location of Human Ortholog: 12q21.1

Cellular Component: endoplasmic reticulum membrane; internal side of plasma membrane; cytoplasmic vesicle membrane; focal adhesion; early endosome; trans-Golgi network; vesicle membrane; endosome; cleavage furrow

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: regulation of exocytosis; intracellular protein transport; metabolic process; regulation of endocytosis; Rab protein signal transduction; positive regulation of receptor-mediated endocytosis
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Research Articles on RAB21

1. High RAB21 expression is associated with glioma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB21 antibody

 Reference Product  PubMed Publications
 ANKRD27 antibody  >2 publications with RAB21 and ANKRD27
 APPL1 antibody  >1 publications with RAB21 and APPL1
 RABGEF1 antibody  >1 publications with RAB21 and RABGEF1

Diseases associated with anti-RAB21 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with RAB21 and Breast Neoplasms
 Liver Diseases Antibodies  >3 publications with RAB21 and Liver Diseases
 Ovarian Neoplasms Antibodies  >2 publications with RAB21 and Ovarian Neoplasms
 Liver Neoplasms Antibodies  >1 publications with RAB21 and Liver Neoplasms
 Brain Diseases Antibodies  >1 publications with RAB21 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with RAB21 and Nervous System Diseases

Organs/Tissues associated with anti-RAB21 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with RAB21 and Liver
 Muscle Antibodies  >2 publications with RAB21 and Muscle
 Bone Antibodies  >1 publications with RAB21 and Bone
 Eye Antibodies  >1 publications with RAB21 and Eye
 Intestine Antibodies  >1 publications with RAB21 and Intestine
 Prostate Antibodies  >1 publications with RAB21 and Prostate
 Brain Antibodies  >1 publications with RAB21 and Brain
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