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SLC1A4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127419
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SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine (1). SLC1A4 mediates the efflux of glutamate from the neuron into the… More details

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Product Overview

Product Name
SLC1A4, Polyclonal Antibody
Full Product Name
SLC1A4 Polyclonal Antibody
Product Gene Name
anti-SLC1A4 antibody
Product Synonym Names
ASCT1; SATT
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
532
OMIM
600229
3D Structure
ModBase 3D Structure for P43007
Species
Human
Route
Synthetic Peptide
Immunogen
A synthetic peptide of human SLC1A4
Calculated Molecular Weight
56kDa

Product Categories/Family for anti-SLC1A4 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SLC1A4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC1A4 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-SLC1A4 antibody

Western blot analysis of extracts of various cell lines, using SLC1A4 antibody at 1:400 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
Rabbit Anti-SLC1A4 Polyclonal Antibody – Cat# MBS127419

Immunohistochemistry (IHC) of anti-SLC1A4 antibody

Immunohistochemistry of paraffin-embedded mouse kidney using SLC1A4 antibody (40x lens).
Rabbit Anti-SLC1A4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127419

Immunohistochemistry (IHC) of anti-SLC1A4 antibody

Immunohistochemistry of paraffin-embedded rat liver using SLC1A4 antibody (40x lens).
Rabbit Anti-SLC1A4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127419

Immunohistochemistry (IHC) of anti-SLC1A4 antibody

Immunohistochemistry of paraffin-embedded human prostate using SLC1A4 antibody (40x lens).
Rabbit Anti-SLC1A4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127419

Immunohistochemistry (IHC) of anti-SLC1A4 antibody

Immunohistochemistry of paraffin-embedded human esophagus using SLC1A4 antibody (40x lens).
Rabbit Anti-SLC1A4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127419

Other Notes

Small volumes of anti-SLC1A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC1A4 purchase

MBS127419 is an antibody targeting SLC1A4. Also known as SLC1A4 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC1A4. It may not necessarily be applicable to this product.

NCBI GI #
1173365
NCBI GeneID
6509
NCBI Accession #
P43007.1
UniProt Primary Accession #
P43007
UniProt Secondary Accession #
B7Z3C0; D6W5F0
UniProt Related Accession #
P43007
NCBI Official Full Name
Neutral amino acid transporter A
NCBI Official Synonym Full Names
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
NCBI Official Symbol
SLC1A4
NCBI Official Synonym Symbols
SATT; ASCT1
UniProt Protein Name
Neutral amino acid transporter A
UniProt Synonym Protein Names
Alanine/serine/cysteine/threonine transporter 1; ASCT-1; SATT; Solute carrier family 1 member 4
Protein Family
Neutral amino acid transporter
UniProt Gene Name
SLC1A4
UniProt Synonym Gene Names
ASCT1; SATT; ASCT-1
UniProt Entry Name
SATT_HUMAN
NCBI Protein Information
neutral amino acid transporter A; ASCT-1; solute carrier family 1 member 4; glutamate/neutral amino acid transporter; alanine/serine/cysteine/threonine transporter 1

UniProt Comments for SLC1A4

SLC1A4: Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p15-p13

Cellular Component: centrosome; cell surface; cell soma; membrane; integral to plasma membrane; dendrite; melanosome; integral to membrane; plasma membrane; intermediate filament; microtubule organizing center

Molecular Function: L-serine transmembrane transporter activity; chloride channel activity; L-threonine transmembrane transporter activity; L-proline transmembrane transporter activity; L-alanine transmembrane transporter activity; L-glutamine transmembrane transporter activity; L-cystine transmembrane transporter activity; sodium:dicarboxylate symporter activity

Biological Process: synaptic transmission, glutamatergic; threonine transport; L-cystine transport; chloride transport; L-serine transport; L-alanine transport; dicarboxylic acid transport; amino acid transport; ion transport; cognition; proline transport; glutamine transport; transmembrane transport
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Research Articles on SLC1A4

1. Na+ interactions with the neutral amino acid transporter ASCT1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC1A4 antibody

 Reference Product  PubMed Publications
 SLC7A5 antibody  >2 publications with SLC1A4 and SLC7A5
 SLC7A1 antibody  >2 publications with SLC1A4 and SLC7A1

Pathways associated with anti-SLC1A4 antibody

 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Diseases associated with anti-SLC1A4 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with SLC1A4 and Nervous System Diseases
 Depressive Disorder Antibodies  >2 publications with SLC1A4 and Depressive Disorder
 Cardiovascular Diseases Antibodies  >2 publications with SLC1A4 and Cardiovascular Diseases
 Inflammation Antibodies  >2 publications with SLC1A4 and Inflammation
 Pain Antibodies  >1 publications with SLC1A4 and Pain
 Atrophy Antibodies  >1 publications with SLC1A4 and Atrophy
 Nerve Degeneration Antibodies  >1 publications with SLC1A4 and Nerve Degeneration
 Edema Antibodies  >1 publications with SLC1A4 and Edema
 Liver Diseases Antibodies  >1 publications with SLC1A4 and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with SLC1A4 and Kidney Diseases

Organs/Tissues associated with anti-SLC1A4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with SLC1A4 and Brain
 Liver Antibodies  >4 publications with SLC1A4 and Liver
 Embryonic Tissue Antibodies  >3 publications with SLC1A4 and Embryonic Tissue
 Kidney Antibodies  >3 publications with SLC1A4 and Kidney
 Blood Antibodies  >3 publications with SLC1A4 and Blood
 Eye Antibodies  >2 publications with SLC1A4 and Eye
 Uterus Antibodies  >2 publications with SLC1A4 and Uterus
 Vascular Antibodies  >2 publications with SLC1A4 and Vascular
 Intestine Antibodies  >2 publications with SLC1A4 and Intestine
 Esophagus Antibodies  >1 publications with SLC1A4 and Esophagus
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