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SLC22A11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9128428
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The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLC22A11, Polyclonal Antibody
Full Product Name
SLC22A11 Polyclonal Antibody
Product Gene Name
anti-SLC22A11 antibody
Product Synonym Names
OAT4; hOAT4; SLC22A11
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
Molecular Weight
Observed MW: 65kDa
Calculated MW: 60kDa
OMIM
607097
3D Structure
ModBase 3D Structure for Q9NSA0
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 40-140 of human SLC22A11 (NP_060954.1).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SLC22A11 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SLC22A11 antibody
WB: 1:500 - 1:1000
EIA: Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.

Western Blot (WB) of anti-SLC22A11 antibody

Western blot analysis of extracts of various cell lines, using SLC22A11 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Rabbit Anti-SLC22A11 Polyclonal Antibody – Cat# MBS9128428

Immunofluorescence (IF) of anti-SLC22A11 antibody

Immunofluorescence analysis of A549 cells using SLC22A11 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-SLC22A11 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS9128428

Western Blot (WB) of anti-SLC22A11 antibody

Western blot analysis of various lysates using SLC22A11 Rabbit pAb at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
Rabbit Anti-SLC22A11 Polyclonal Antibody, Western Blot (WB) – Cat# MBS9128428

Other Notes

Small volumes of anti-SLC22A11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC22A11 purchase

MBS9128428 is an antibody targeting SLC22A11. Also known as SLC22A11 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC22A11. It may not necessarily be applicable to this product.

NCBI GI #
808175981
NCBI GeneID
55867
NCBI Accession #
NP_001294914.1
UniProt Primary Accession #
Q9NSA0
UniProt Secondary Accession #
Q53GR2; Q6ZP72; Q8NBU4; A8K426
UniProt Related Accession #
Q9NSA0
GenBank Nucleotide #
NM_001307985.1
NCBI Official Full Name
solute carrier family 22 member 11 isoform 2
NCBI Official Synonym Full Names
solute carrier family 22 (organic anion/urate transporter), member 11
NCBI Official Symbol
SLC22A11
NCBI Official Synonym Symbols
OAT4; hOAT4
UniProt Protein Name
Solute carrier family 22 member 11
UniProt Synonym Protein Names
Organic anion transporter 4
Protein Family
Solute carrier family
UniProt Gene Name
SLC22A11
UniProt Synonym Gene Names
OAT4
UniProt Entry Name
S22AB_HUMAN
NCBI Protein Information
solute carrier family 22 member 11

UniProt Comments for SLC22A11

SLC22A11: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: integral to plasma membrane; apical plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; inorganic anion exchanger activity; organic anion transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity

Biological Process: urate metabolic process; transmembrane transport; organic anion transport
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Research Articles on SLC22A11

1. SLC22A11 at the basal plasma membrane of human placental syncytiotrophoblasts plays a predominant role in the uptake of 16alpha-OH DHEAS for placental estriol synthesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC22A11 antibody

 Reference Product  PubMed Publications
 SLC2A9 antibody  >13 publications with SLC22A11 and SLC2A9
 SLC17A1 antibody  >11 publications with SLC22A11 and SLC17A1
 SLC16A9 antibody  >8 publications with SLC22A11 and SLC16A9
 SLC17A3 antibody  >5 publications with SLC22A11 and SLC17A3
 ABCC4 antibody  >4 publications with SLC22A11 and ABCC4

Pathways associated with anti-SLC22A11 antibody

 Products by Pathway  Pathway Diagram
 Organic Anion Transport Pathway antibodies  Organic Anion Transport Pathway Diagram
 Organic Cation/anion/zwitterion Transport Pathway antibodies  Organic Cation/anion/zwitterion Transport Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-SLC22A11 antibody

 Disease Name  Pubmed Publications
 Arthritis Antibodies  >11 publications with SLC22A11 and Arthritis
 Cardiovascular Diseases Antibodies  >7 publications with SLC22A11 and Cardiovascular Diseases
 Hypertension Antibodies  >6 publications with SLC22A11 and Hypertension
 Kidney Diseases Antibodies  >6 publications with SLC22A11 and Kidney Diseases
 Brain Diseases Antibodies  >3 publications with SLC22A11 and Brain Diseases
 Renal Insufficiency Antibodies  >2 publications with SLC22A11 and Renal Insufficiency
 Liver Diseases Antibodies  >2 publications with SLC22A11 and Liver Diseases
 Arthritis, Rheumatoid Antibodies  >1 publications with SLC22A11 and Arthritis, Rheumatoid
 Fatty Liver Antibodies  >1 publications with SLC22A11 and Fatty Liver
 Kidney Tubular Necrosis, Acute Antibodies  >1 publications with SLC22A11 and Kidney Tubular Necrosis, Acute

Organs/Tissues associated with anti-SLC22A11 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >27 publications with SLC22A11 and Kidney
 Placenta Antibodies  >10 publications with SLC22A11 and Placenta
 Liver Antibodies  >7 publications with SLC22A11 and Liver
 Brain Antibodies  >1 publications with SLC22A11 and Brain
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