Rabbit Anti-SNCB Polyclonal Antibody – Cat# MBS9129790

SNCB Antibody – Rabbit Polyclonal

Name: SNCB Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9129790
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9129790

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SNCB, Polyclonal Antibody

Full Product Name

SNCB Polyclonal Antibody

Product Gene Name

anti-SNCB antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C. Avoid freeze / thaw cycles.

Molecular Weight

Calculated MW: 14kDa
Molecular Weight: 134

OMIM

602569

3D Structure

ModBase 3D Structure for Q16143

Immunogen

Recombinant protein of human SNCB

Product Categories/Family for anti-SNCB antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SNCB antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)

Application Notes for anti-SNCB antibody

WB: 1:200 - 1:2000, IHC1:10 - 1:100, IF: 1:10 - 1:100, FC: 1:20 - 1:50

Other Notes

Small volumes of anti-SNCB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNCB purchase

MBS9129790 is an antibody targeting SNCB. Also known as SNCB Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SNCB. It may not necessarily be applicable to this product.

NCBI GI #

48255903

NCBI GeneID

6620

NCBI Accession #

NP_001001502.1

UniProt Primary Accession #

Q16143

UniProt Secondary Accession #

Q6IAX7

UniProt Related Accession #

Q16143

GenBank Nucleotide #

NM_001001502.2

NCBI Official Full Name

beta-synuclein isoform 1

NCBI Official Synonym Full Names

synuclein beta

NCBI Official Symbol

SNCB

UniProt Protein Name

Beta-synuclein

Protein Family

Beta-synuclein

UniProt Gene Name

SNCB

UniProt Entry Name

SYUB_HUMAN

NCBI Protein Information

beta-synuclein

NCBI Summary for SNCB

This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

UniProt Comments for SNCB

SNCB: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May play a role in neuronal plasticity, is abundant in neurofibrillary lesions of Alzheimer's patients. Highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: cell soma; cytoplasm; Golgi apparatus; growth cone; inclusion body; mitochondrion; nucleoplasm; terminal button

Molecular Function: alpha-tubulin binding; beta-tubulin binding; calcium ion binding; phospholipase inhibitor activity

Biological Process: dopamine metabolic process; negative regulation of catalytic activity; negative regulation of neuron apoptosis; synapse organization and biogenesis; synaptic transmission

Disease: Dementia, Lewy Body

Research Articles on SNCB

1. The differing aggregation propensities of alpha-synuclein and beta-synuclein are associated with differences in the degree of residual structure in the C-terminus coupled to the shorter separation between the N- and C-termini in beta-synuclein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SNCB antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>48 publications with SNCB and Brain Diseases
Lewy Body Disease Antibodies	>21 publications with SNCB and Lewy Body Disease
Disease Models, Animal Antibodies	>9 publications with SNCB and Disease Models, Animal
Hyperplasia Antibodies	>4 publications with SNCB and Hyperplasia
Neurobehavioral Manifestations Antibodies	>2 publications with SNCB and Neurobehavioral Manifestations
Fibrosis Antibodies	>2 publications with SNCB and Fibrosis
Lung Diseases Antibodies	>1 publications with SNCB and Lung Diseases
Depressive Disorder Antibodies	>1 publications with SNCB and Depressive Disorder
Poisoning Antibodies	>1 publications with SNCB and Poisoning
Kidney Diseases Antibodies	>1 publications with SNCB and Kidney Diseases

Organs/Tissues associated with anti-SNCB antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>73 publications with SNCB and Nerve
Brain Antibodies	>65 publications with SNCB and Brain
Eye Antibodies	>1 publications with SNCB and Eye