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SRSF6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9440242

The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of… More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SRSF6, Polyclonal Antibody
Full Product Name
SRSF6 Polyclonal Conjugated Antibody
Product Gene Name
anti-SRSF6 antibody
Product Synonym Names
SRSF6 Conjugated Antibody; SRSF6; B52; HEL-S-91; SFRS6; SRP55; serine/arginine-rich splicing factor 6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Purity/Purification
Affinity purification
Preparation and Storage
Store at 4 degree C for 6 months.
Molecular Weight
39,587 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (42086504..42092245). Location: 20q12-q13.1
OMIM
601944
3D Structure
ModBase 3D Structure for Q13247
Immunogen
A synthetic peptide of human SRSF6 (NP_006266.2).
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Applications Tested/Suitable for anti-SRSF6 antibody
Most Applications
Application Notes for anti-SRSF6 antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-SRSF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRSF6 purchase

MBS9440242 is an antibody targeting SRSF6. Also known as SRSF6 Polyclonal Conjugated Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRSF6. It may not necessarily be applicable to this product.

NCBI GI #
20127499
NCBI GeneID
6431
NCBI Accession #
NP_006266.2
UniProt Primary Accession #
Q13247
UniProt Secondary Accession #
Q13244; Q13245; Q96J06; Q9UJB8; Q9Y3N7; B7Z6J3; E1P5W6
UniProt Related Accession #
Q13247; Q59GY3
GenBank Nucleotide #
NM_006275.5
NCBI Official Full Name
serine/arginine-rich splicing factor 6
NCBI Official Synonym Full Names
serine/arginine-rich splicing factor 6
NCBI Official Symbol
SRSF6
NCBI Official Synonym Symbols
B52; SFRS6; SRP55; MGC5045; FLJ08061
UniProt Protein Name
Serine/arginine-rich splicing factor 6
UniProt Synonym Protein Names
Pre-mRNA-splicing factor SRP55; Splicing factor, arginine/serine-rich 6
Protein Family
Serine/arginine-rich splicing factor
UniProt Gene Name
SRSF6
UniProt Synonym Gene Names
SFRS6; SRP55
UniProt Entry Name
SRSF6_HUMAN
NCBI Protein Information
serine/arginine-rich splicing factor 6; OTTHUMP00000031020; SR splicing factor 6; pre-mRNA splicing factor SRP55; pre-mRNA-splicing factor SRP55; arginine/serine-rich splicing factor 6; splicing factor, arginine/serine-rich 6; splicing factor, arginine/se

UniProt Comments for SRSF6

SFRS6: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA-binding; RNA splicing

Chromosomal Location of Human Ortholog: 20q12-q13.1

Cellular Component: nucleoplasm; nuclear speck

Molecular Function: RNA binding; nucleotide binding

Biological Process: alternative nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA splice site selection; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; negative regulation of keratinocyte differentiation; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; regulation of alternative nuclear mRNA splicing, via spliceosome
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Research Articles on SRSF6

1. Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SRSF6 antibody

 Reference Product  PubMed Publications
 SRSF4 antibody  >2 publications with SRSF6 and SRSF4

Pathways associated with anti-SRSF6 antibody

 Products by Pathway  Pathway Diagram
 Cleavage Of Growing Transcript In The Termination Region Pathway antibodies  Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
 Formation And Maturation Of MRNA Transcript Pathway antibodies  Formation And Maturation Of MRNA Transcript Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 RNA Polymerase II Transcription Pathway antibodies  RNA Polymerase II Transcription Pathway Diagram
 RNA Polymerase II Transcription Termination Pathway antibodies  RNA Polymerase II Transcription Termination Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Transcription Pathway antibodies  Transcription Pathway Diagram
 Transport Of Mature Transcript To Cytoplasm Pathway antibodies  Transport Of Mature Transcript To Cytoplasm Pathway Diagram

Diseases associated with anti-SRSF6 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with SRSF6 and Neoplasms
 Brain Diseases Antibodies  >1 publications with SRSF6 and Brain Diseases
 Fetal Diseases Antibodies  >1 publications with SRSF6 and Fetal Diseases
 Skin Diseases Antibodies  >1 publications with SRSF6 and Skin Diseases
 Gastrointestinal Neoplasms Antibodies  >1 publications with SRSF6 and Gastrointestinal Neoplasms
 Glioblastoma Antibodies  >1 publications with SRSF6 and Glioblastoma
 Colonic Neoplasms Antibodies  >1 publications with SRSF6 and Colonic Neoplasms
 Pancreatic Neoplasms Antibodies  >1 publications with SRSF6 and Pancreatic Neoplasms
 Adenocarcinoma Antibodies  >1 publications with SRSF6 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >1 publications with SRSF6 and Cardiovascular Diseases

Organs/Tissues associated with anti-SRSF6 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with SRSF6 and Blood
 Brain Antibodies  >2 publications with SRSF6 and Brain
 Muscle Antibodies  >2 publications with SRSF6 and Muscle
 Eye Antibodies  >1 publications with SRSF6 and Eye
 Uncharacterized Tissue Antibodies  >1 publications with SRSF6 and Uncharacterized Tissue
 Mouth Antibodies  >1 publications with SRSF6 and Mouth
 Embryonic Tissue Antibodies  >1 publications with SRSF6 and Embryonic Tissue
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