Rabbit Anti-SYNJ1 Polyclonal Antibody – Cat# MBS6459625

SYNJ1 Antibody – Rabbit Polyclonal

Name: SYNJ1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6459625
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6459625

MBS6459625 is an antibody targeting SYNJ1. Also known as SYNJ1 (Synaptojanin-1, Synaptic inositol 1,5-trisphosphate 5-Phosphatase 1, SYNJ1, KIAA0910) (MaxLight 750). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SYNJ1, Polyclonal Antibody

Full Product Name

SYNJ1 (Synaptojanin-1, Synaptic inositol 1,5-trisphosphate 5-Phosphatase 1, SYNJ1, KIAA0910) (MaxLight 750)

Product Gene Name

anti-SYNJ1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes SYNJ1. Species Crossreactivity: human, mouse, rat

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

604297

3D Structure

ModBase 3D Structure for O43426

Immunogen

KLH conjugated synthetic peptide corresponding to aa1148-1182 at the C-terminal region of human SYNJ1.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-SYNJ1 antibody

Antibodies; Enzymes

Applications Tested/Suitable for anti-SYNJ1 antibody

Western Blot (WB)

Application Notes for anti-SYNJ1 antibody

WB: 1:1000-1:2000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SYNJ1 antibody

Haffner C., et al. FEBS Lett. 419:175-180(1997). Nagase T., et al. DNA Res. 5:355-364(1998). Nakajima D., et al. DNA Res. 9:99-106(2002). Hattori M., et al. Nature 405:311-319(2000). Cestra G., et al. J. Biol. Chem. 274:32001-32007(1999).

Other Notes

Small volumes of anti-SYNJ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SYNJ1. It may not necessarily be applicable to this product.

NCBI GI #

215273894

NCBI GeneID

8867

UniProt Primary Accession #

O43426

UniProt Related Accession #

O43426

NCBI Official Full Name

Synaptojanin-1

NCBI Official Synonym Full Names

synaptojanin 1

NCBI Official Symbol

SYNJ1

NCBI Official Synonym Symbols

EIEE53; INPP5G; PARK20

UniProt Protein Name

Synaptojanin-1

UniProt Synonym Protein Names

Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1

Protein Family

Synaptojanin

UniProt Gene Name

SYNJ1

UniProt Synonym Gene Names

KIAA0910

UniProt Entry Name

SYNJ1_HUMAN

NCBI Protein Information

synaptojanin-1

NCBI Summary for SYNJ1

This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

UniProt Comments for SYNJ1

SYNJ1: Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis. Belongs to the synaptojanin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - inositol phosphate; Phosphatase, lipid; Motility/polarity/chemotaxis; Vesicle; EC 3.1.3.36

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: membrane coat; cytosol

Molecular Function: RNA binding; phosphoinositide 5-phosphatase activity; nucleotide binding; inositol-polyphosphate 5-phosphatase activity

Biological Process: inositol phosphate metabolic process; neurotransmitter transport; phospholipid metabolic process; inositol phosphate dephosphorylation; synaptic vesicle endocytosis; phosphatidylinositol biosynthetic process; synaptic vesicle transport; phosphoinositide dephosphorylation; synaptic vesicle uncoating; phosphatidylinositol metabolic process; synaptic vesicle priming; phosphate metabolic process

Disease: Parkinson Disease 20, Early-onset

Research Articles on SYNJ1

1. SYNJ1 contributes to memory deficits in the aging hippocampus in all forms of Alzheimer's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SYNJ1 antibody

Reference Product	PubMed Publications
ITSN1 antibody	>2 publications with SYNJ1 and ITSN1
SH3GL2 antibody	>2 publications with SYNJ1 and SH3GL2
BIN1 antibody	>1 publications with SYNJ1 and BIN1
AP2A1 antibody	>1 publications with SYNJ1 and AP2A1
DNM1 antibody	>1 publications with SYNJ1 and DNM1
EPS15 antibody	>1 publications with SYNJ1 and EPS15

Pathways associated with anti-SYNJ1 antibody

Products by Pathway	Pathway Diagram
1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies	1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies	1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies	D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies	D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
EPHB Forward Signaling Pathway antibodies	EPHB Forward Signaling Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram

Diseases associated with anti-SYNJ1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>20 publications with SYNJ1 and Nervous System Diseases
Seizures Antibodies	>8 publications with SYNJ1 and Seizures
Neurobehavioral Manifestations Antibodies	>6 publications with SYNJ1 and Neurobehavioral Manifestations
Abnormalities, Multiple Antibodies	>5 publications with SYNJ1 and Abnormalities, Multiple
Congenital Abnormalities Antibodies	>5 publications with SYNJ1 and Congenital Abnormalities
Cognition Disorders Antibodies	>3 publications with SYNJ1 and Cognition Disorders
Ataxia Antibodies	>1 publications with SYNJ1 and Ataxia
Neoplasm Metastasis Antibodies	>1 publications with SYNJ1 and Neoplasm Metastasis
Kidney Diseases Antibodies	>1 publications with SYNJ1 and Kidney Diseases
Personality Disorders Antibodies	>1 publications with SYNJ1 and Personality Disorders

Organs/Tissues associated with anti-SYNJ1 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>22 publications with SYNJ1 and Nerve
Brain Antibodies	>21 publications with SYNJ1 and Brain
Eye Antibodies	>4 publications with SYNJ1 and Eye
Blood Antibodies	>2 publications with SYNJ1 and Blood
Muscle Antibodies	>2 publications with SYNJ1 and Muscle
Bone Antibodies	>1 publications with SYNJ1 and Bone
Kidney Antibodies	>1 publications with SYNJ1 and Kidney
Bone Marrow Antibodies	>1 publications with SYNJ1 and Bone Marrow
Lung Antibodies	>1 publications with SYNJ1 and Lung
Embryonic Tissue Antibodies	>1 publications with SYNJ1 and Embryonic Tissue