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CD248 (TEM1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9460928

The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal… More details

$535 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TEM1 CD248, Polyclonal Antibody
Full Product Name
TEM1 CD248 Antibody PE Conjugated
Product Gene Name
Product Synonym Gene Name
CD248
Product Synonym Names
TEM1; CD164L1; Endosialin; Tumor endothelial marker 1; CD248; TEM1 CD248
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.1M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
Purity/Purification
Purified by Protein A
Concentration
1mgml (lot specific)
Preparation and Storage
Store at -20° for one year. Avoid repeated freeze/thaw cycles.
Molecular Weight
757
OMIM
606064
3D Structure
ModBase 3D Structure for Q9HCU0
Conjugation
PE
Excitation Emission
480,565nm 578nm
Immunogen
KLH conjugated synthetic peptide aa 280-320 757 derived from human TEM 1
Cell Localization
Extracellular
Applications Tested/Suitable for anti-TEM1 antibody
Immunofluorescence (IF)
Application Notes for anti-TEM1 antibody
IF: 1:50-200

Other Notes

Small volumes of anti-TEM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TEM1 purchase

MBS9460928 is an antibody targeting TEM1. Also known as TEM1 CD248 Antibody PE Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TEM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Endosialin
NCBI Official Synonym Full Names
CD248 molecule, endosialin
NCBI Official Symbol
CD248
NCBI Official Synonym Symbols
TEM1; CD164L1
UniProt Protein Name
Endosialin
UniProt Synonym Protein Names
Tumor endothelial marker 1; CD_antigen: CD248
UniProt Gene Name
CD248
UniProt Synonym Gene Names
CD164L1; TEM1
UniProt Entry Name
CD248_HUMAN
NCBI Protein Information
endosialin; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; tumor endothelial marker 1

UniProt Comments for TEM1

CD248: May play a role in tumor angiogenesis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: proteinaceous extracellular matrix; cytoplasm; integral to membrane

Molecular Function: extracellular matrix binding; calcium ion binding; carbohydrate binding

Biological Process: cell migration; positive regulation of cell proliferation; anatomical structure regression; lymph node development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TEM1 antibody

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