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THG1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2563033

The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
THG1L, Polyclonal Antibody
Full Product Name
THG1L Polyclonal Antibody
Product Gene Name
Product Synonym Names
ICF45; Interphase cytoplasmic foci protein 45; Probable tRNA(His) guanylyltransferase; THG1; THG1L; TRNA histidine guanylyltransferase 1 like (S. cerevisiae); TRNA-histidine guanylyltransferase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.9mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
3D Structure
ModBase 3D Structure for Q9NWX6
Immunogen
Fusion protein of human THG1L
Conjugation
Unconjugated

Product Categories/Family for anti-THG1L antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-THG1L antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-THG1L antibody
IHC: 1:50-1:200
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-THG1L antibody

Immunohistochemistry of paraffin-embedded Human tonsil tissue using THG1L Polyclonal Antibody at dilution of 1:50(×200)
Rabbit Anti-THG1L Polyclonal Antibody – Cat# MBS2563033

Other Notes

Small volumes of anti-THG1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for THG1L purchase

MBS2563033 is an antibody targeting THG1L. Also known as THG1L Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for THG1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Probable tRNA(His) guanylyltransferase
NCBI Official Synonym Full Names
tRNA-histidine guanylyltransferase 1 like
NCBI Official Symbol
THG1L
NCBI Official Synonym Symbols
ICF45; IHG-1; hTHG1
UniProt Protein Name
Probable tRNA(His) guanylyltransferase
UniProt Synonym Protein Names
Interphase cytoplasmic foci protein 45; tRNA-histidine guanylyltransferase
UniProt Gene Name
THG1L
UniProt Synonym Gene Names
ICF45
UniProt Entry Name
THG1_HUMAN
NCBI Protein Information
probable tRNA(His) guanylyltransferase

UniProt Comments for THG1L

ICF45: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis. Belongs to the tRNA(His) guanylyltransferase family.

Protein type: EC 2.7.7.79; Cell cycle regulation; Mitochondrial; Transferase

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: mitochondrion; cytoplasm

Molecular Function: identical protein binding; tRNA guanylyltransferase activity; GTP binding; magnesium ion binding; ATP binding; tRNA binding

Biological Process: tRNA processing; tRNA modification; protein homotetramerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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