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TP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240321

MBS240321 is an antibody targeting TP1. Also known as Rabbit Polyclonal to Human TP1 / TEP1. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TP1 / TEP1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TP1 / TEP1
Product Gene Name
Product Synonym Gene Name
TEP1
Product Synonym Names
Anti-TP1 / TEP1 Antibody (N-Terminus) IHC-plus; TEP1; p80 telomerase homolog; Telomerase protein 1; TLP1; TROVE domain family; member 1; TROVE1; VAULT2; p240; Telomerase protein component 1; TP1; Human TP1; TEP1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
20 amino acid peptide from near the amino terminus of human TP1.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
289,578 Da
OMIM
601686
3D Structure
ModBase 3D Structure for Q99973
Target Species
Human
Immunogen Description
Synthetic peptide from human TEP1.
Immunogen Type
Synthetic peptide
Immunogen
TP1 / TEP1 antibody was raised against synthetic peptide from human TEP1.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-TP1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TP1 antibody
IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-TP1 antibody

Anti-TEP1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TP1 Polyclonal Antibody – Cat# MBS240321

Immunohistochemistry (IHC) of anti-TP1 antibody

Anti-TEP1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS240321

Immunofluorescence (IF) of anti-TP1 antibody

Immunofluorescence of TP-1 in Human Lung cells with TP-1 antibody at 20 ug/ml.
Rabbit Anti-TP1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS240321

Western Blot (WB) of anti-TP1 antibody

Western blot of TP1 in human kidney tissue lysate with TP1 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-TP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS240321

Other Notes

Small volumes of anti-TP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
telomerase protein component 1
NCBI Official Synonym Full Names
telomerase-associated protein 1
NCBI Official Symbol
TEP1
NCBI Official Synonym Symbols
TP1; TLP1; p240; TROVE1; VAULT2
UniProt Protein Name
Telomerase protein component 1
UniProt Synonym Protein Names
Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog
UniProt Gene Name
TEP1
UniProt Synonym Gene Names
TLP1; TP1; Telomerase protein 1
UniProt Entry Name
TEP1_HUMAN
NCBI Protein Information
telomerase protein component 1; telomerase protein 1; p80 telomerase homolog; TROVE domain family, member 1

NCBI Summary for TP1

This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. [provided by RefSeq, Jul 2008]

UniProt Comments for TP1

TEP1: Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: chromosome, telomeric region; nuclear matrix; cytoplasm; telomerase holoenzyme complex; ribonucleoprotein complex

Molecular Function: telomerase activity; RNA binding; ATP binding

Biological Process: RNA-dependent DNA replication; telomere maintenance via recombination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TP1 antibody

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