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TPH2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8292403

MBS8292403 is an antibody targeting TPH2. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to TPH2 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TPH2, Polyclonal Antibody
Full Product Name
Anti-TPH2 Antibody
Product Gene Name
Product Synonym Names
NTPH; Tryptophan 5-hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
Purified by immunogen affinity chromatography
Specificity
Recognizes endogenous levels of TPH2 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
56,242 Da
OMIM
AY098914 mRNA
3D Structure
ModBase 3D Structure for Q8IWU9
Immunogen
Recombinant full length protein of human TPH2
Applications Tested/Suitable for anti-TPH2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-TPH2 antibody
WB: 1/500 - 1/2000
IHC: 1/50 - 1/200
IF/ICC: 1/50 - 1/200

Western Blot (WB) of anti-TPH2 antibody

Western blot analysis of TPH2 expression in mouse skeletal muscle (A), rat brain (B) whole cell lysates.
Rabbit Anti-TPH2 Polyclonal Antibody – Cat# MBS8292403

Immunofluorescence (IF) of anti-TPH2 antibody

Immunofluorescent analysis of TPH2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Rabbit Anti-TPH2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS8292403

Other Notes

Small volumes of anti-TPH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TPH2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tryptophan 5-hydroxylase 2
NCBI Official Synonym Full Names
tryptophan hydroxylase 2
NCBI Official Symbol
TPH2
NCBI Official Synonym Symbols
NTPH; ADHD7
UniProt Protein Name
Tryptophan 5-hydroxylase 2
UniProt Synonym Protein Names
Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2
UniProt Gene Name
TPH2
UniProt Synonym Gene Names
NTPH
NCBI Protein Information
tryptophan 5-hydroxylase 2

NCBI Summary for TPH2

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TPH2 antibody

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