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TRAPPC9/NIBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7605186

MBS7605186 is an antibody targeting TRAPPC9/NIBP. Also known as TRAPPC9/NIBP Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TRAPPC9/NIBP, Polyclonal Antibody
Full Product Name
TRAPPC9/NIBP Rabbit Polyclonal
Product Gene Name
anti-TRAPPC9/NIBP antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
127,607 Da
OMIM
611966
Immunogen
Trafficking protein particle complex 9
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-TRAPPC9/NIBP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-TRAPPC9/NIBP antibody

Immunohistochemistry of paraffin-embedded human kidney using MBS7605186 (TRAPPC9,NIBP antibody) at dilution of 1:50
Rabbit Anti-TRAPPC9/NIBP Polyclonal Antibody – Cat# MBS7605186

Western Blot (WB) of anti-TRAPPC9/NIBP antibody

mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS7605186 (TRAPPC9,NIBP antibody) at dilution of 1:800
Rabbit Anti-TRAPPC9/NIBP Polyclonal Antibody, Western Blot (WB) – Cat# MBS7605186

Other Notes

Small volumes of anti-TRAPPC9/NIBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAPPC9/NIBP. It may not necessarily be applicable to this product.

NCBI GI #
1011750901
NCBI GeneID
83696
NCBI Accession #
NP_001308575.1
UniProt Secondary Accession #
Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96SL2; Q9BQA2
UniProt Related Accession #
Q96Q05
GenBank Nucleotide #
NM_001321646.1
NCBI Official Full Name
trafficking protein particle complex subunit 9 isoform c
NCBI Official Synonym Full Names
trafficking protein particle complex 9
NCBI Official Symbol
TRAPPC9
NCBI Official Synonym Symbols
T1; IBP; NIBP; MRT13; TRS120; IKBKBBP
UniProt Protein Name
Trafficking protein particle complex subunit 9
UniProt Synonym Protein Names
NIK- and IKBKB-binding protein; Tularik gene 1 protein
UniProt Gene Name
TRAPPC9
UniProt Synonym Gene Names
KIAA1882; NIBP
UniProt Entry Name
TPPC9_HUMAN
NCBI Protein Information
trafficking protein particle complex subunit 9

NCBI Summary for TRAPPC9/NIBP

This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

UniProt Comments for TRAPPC9/NIBP

NIBP: Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Defects in TRAPPC9 are the cause of mental retardation autosomal recessive type 13 (MRT13). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals. Belongs to the NIBP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: cytosol; endoplasmic reticulum; Golgi membrane; trans-Golgi network

Biological Process: activation of NF-kappaB transcription factor; cerebral cortex development; COPII coating of Golgi vesicle; neuron differentiation

Disease: Mental Retardation, Autosomal Recessive 13
Show more

Research Articles on TRAPPC9/NIBP

1. Data identified important roles of NIBP in promoting tumorigenesis via NFkappaBeta signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TRAPPC9/NIBP antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies  COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Transport To The Golgi And Subsequent Modification Pathway antibodies  Transport To The Golgi And Subsequent Modification Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram

Diseases associated with anti-TRAPPC9/NIBP antibody

 Disease Name  Pubmed Publications
 Neurobehavioral Manifestations Antibodies  >12 publications with TRAPPC9/NIBP and Neurobehavioral Manifestations
 Breast Neoplasms Antibodies  >3 publications with TRAPPC9/NIBP and Breast Neoplasms
 Necrosis Antibodies  >2 publications with TRAPPC9/NIBP and Necrosis
 Cardiovascular Diseases Antibodies  >1 publications with TRAPPC9/NIBP and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >1 publications with TRAPPC9/NIBP and Disease Models, Animal
 Mental Retardation, Autosomal Recessive 13 Antibodies  >1 publications with TRAPPC9/NIBP and Mental Retardation, Autosomal Recessive 13

Organs/Tissues associated with anti-TRAPPC9/NIBP antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with TRAPPC9/NIBP and Brain
 Skin Antibodies  >1 publications with TRAPPC9/NIBP and Skin
 Liver Antibodies  >1 publications with TRAPPC9/NIBP and Liver
 Intestine Antibodies  >1 publications with TRAPPC9/NIBP and Intestine
 Blood Antibodies  >1 publications with TRAPPC9/NIBP and Blood
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