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TWIST2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7126616

MBS7126616 is an antibody targeting TWIST2. Also known as TWIST2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TWIST2, Polyclonal Antibody
Full Product Name
TWIST2 Antibody
Product Gene Name
Product Synonym Names
Twist family bHLH Transcription factor 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Purity/Purification
Antigen Affinity Purification
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
18,124 Da
3D Structure
ModBase 3D Structure for Q8WVJ9
Immunogen
Full length of human TWIST2
Immunogen Species
Human
Conjugate
Non-conjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TWIST2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-TWIST2 antibody
ELISA: 1:2000-1:5000
IHC: 1:25-1:100

Immunohistochemistry (IHC)-Paraffin of anti-TWIST2 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126616(TWIST2 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
Rabbit Anti-TWIST2 Polyclonal Antibody – Cat# MBS7126616

Other Notes

Small volumes of anti-TWIST2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TWIST2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
twist-related protein 2
NCBI Official Synonym Full Names
twist family bHLH transcription factor 2
NCBI Official Symbol
TWIST2
NCBI Official Synonym Symbols
AMS; FFDD3; BBRSAY; DERMO1; SETLSS; bHLHa39
UniProt Protein Name
Twist-related protein 2
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 39; bHLHa39; Dermis-expressed protein 1; Dermo-1
Protein Family
UniProt Gene Name
TWIST2
UniProt Synonym Gene Names
BHLHA39; DERMO1; bHLHa39; Dermo-1
NCBI Protein Information
twist-related protein 2

NCBI Summary for TWIST2

The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014]
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UniProt Comments for TWIST2

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TWIST2 antibody

 Reference Product  PubMed Publications
 SREBF1 antibody  >1 publications with TWIST2 and SREBF1
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