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UNC45A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7605491

MBS7605491 is an antibody targeting UNC45A. Also known as UNC45A Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
UNC45A, Polyclonal Antibody
Full Product Name
UNC45A Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
24,689 Da
OMIM
611219
Immunogen
Unc-45 homolog A (C. elegans)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-UNC45A antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

Immunohistochemistry (IHC) of anti-UNC45A antibody

Immunohistochemistry of paraffin-embedded human stomach using MBS7605491 (UNC45A antibody) at dilution of 1:100
Rabbit Anti-UNC45A Polyclonal Antibody – Cat# MBS7605491

Western Blot (WB) of anti-UNC45A antibody

K562 cells were subjected to SDS PAGE followed by western blot with MBS7605491 (UNC45A antibody) at dilution of 1:1000
Rabbit Anti-UNC45A Polyclonal Antibody, Western Blot (WB) – Cat# MBS7605491

Other Notes

Small volumes of anti-UNC45A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UNC45A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
UNC45A protein, partial
NCBI Official Synonym Full Names
unc-45 myosin chaperone A
NCBI Official Symbol
UNC45A
NCBI Official Synonym Symbols
SMAP1; SMAP-1; GCUNC45; UNC-45A; GC-UNC45; GCUNC-45; IRO039700
UniProt Protein Name
Protein unc-45 homolog A
UniProt Synonym Protein Names
GCUNC-45; Smooth muscle cell-associated protein 1; SMAP-1
Protein Family
UniProt Gene Name
UNC45A
UniProt Synonym Gene Names
SMAP1; Unc-45A; SMAP-1
UniProt Entry Name
UN45A_HUMAN
NCBI Protein Information
protein unc-45 homolog A

NCBI Summary for UNC45A

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008]
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UniProt Comments for UNC45A

UNC45A: Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 15q26.1

Cellular Component: nucleus; perinuclear region of cytoplasm

Molecular Function: Hsp90 protein binding; protein binding

Biological Process: cell differentiation; muscle development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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