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UNC5A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8233328

MBS8233328 is an antibody targeting UNC5A. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to UNC5A More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UNC5A, Polyclonal Antibody
Full Product Name
Anti-UNC5A Antibody
Product Gene Name
Product Synonym Names
KIAA1976; UNC5H1; Netrin receptor UNC5A; Protein unc-5 homolog 1; Protein unc-5 homolog A
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of UNC5A protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
UNC5A peptide (MBS8215291) is used for blocking the activity of UNC5A antibody (MBS8233328)
Molecular Weight
88,640 Da
OMIM
607869
3D Structure
ModBase 3D Structure for Q6ZN44
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human UNC5A. The exact sequence is proprietary.
Applications Tested/Suitable for anti-UNC5A antibody
Western Blot (WB)
Application Notes for anti-UNC5A antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-UNC5A antibody

Western blot analysis of UNC5A expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates.
Rabbit Anti-UNC5A Polyclonal Antibody – Cat# MBS8233328

Other Notes

Small volumes of anti-UNC5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UNC5A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
netrin receptor UNC5A
NCBI Official Synonym Full Names
unc-5 netrin receptor A
NCBI Official Symbol
UNC5A
NCBI Official Synonym Symbols
UNC5H1
UniProt Protein Name
Netrin receptor UNC5A
UniProt Synonym Protein Names
Protein unc-5 homolog 1; Protein unc-5 homolog A
Protein Family
UniProt Gene Name
UNC5A
UniProt Synonym Gene Names
KIAA1976; UNC5H1
UniProt Entry Name
UNC5A_HUMAN
NCBI Protein Information
netrin receptor UNC5A

NCBI Summary for UNC5A

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004]

UniProt Comments for UNC5A

UNC5A: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Belongs to the unc-5 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell development/differentiation

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: plasma membrane; integral to membrane

Biological Process: axon guidance; positive regulation of apoptosis; anterior/posterior axon guidance
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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