Rabbit Anti-VDAC2 Polyclonal Antibody – Cat# MBS8570958

VDAC2 Antibody – Rabbit Polyclonal

Name: VDAC2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8570958
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8570958

This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the… More details

$380 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VDAC2, Polyclonal Antibody

Full Product Name

VDAC2 Polyclonal Antibody

Product Gene Name

anti-VDAC2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.

Purity/Purification

Affinity Purification

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

Molecular Weight

30kDa; 31kDa; 33kDa

OMIM

193245

3D Structure

ModBase 3D Structure for P45880

Immunogen

Recombinant protein of human VDAC2

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-VDAC2 antibody

Western Blot (WB)

Application Notes for anti-VDAC2 antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-VDAC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VDAC2 purchase

MBS8570958 is an antibody targeting VDAC2. Also known as VDAC2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VDAC2. It may not necessarily be applicable to this product.

NCBI GI #

158518391

NCBI GeneID

7417

NCBI Accession #

P45880.2

UniProt Primary Accession #

P45880

UniProt Related Accession #

P45880

NCBI Official Full Name

Voltage-dependent anion-selective channel protein 2

NCBI Official Synonym Full Names

voltage dependent anion channel 2

NCBI Official Symbol

VDAC2

NCBI Official Synonym Symbols

POR

UniProt Protein Name

Voltage-dependent anion-selective channel protein 2

UniProt Synonym Protein Names

Outer mitochondrial membrane protein porin 2

Protein Family

Mitochondrial outer membrane protein porin

UniProt Gene Name

VDAC2

UniProt Synonym Gene Names

VDAC-2; hVDAC2

UniProt Entry Name

VDAC2_HUMAN

NCBI Protein Information

voltage-dependent anion-selective channel protein 2

UniProt Comments for VDAC2

VDAC2: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. Interacts with hexokinases. Expressed in all tissues examined. Belongs to the eukaryotic mitochondrial porin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Mitochondrial; Channel, misc.

Chromosomal Location of Human Ortholog: 10q22

Cellular Component: pore complex; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; nucleus

Molecular Function: protein binding; nucleotide binding; voltage-gated anion channel activity; porin activity

Biological Process: negative regulation of protein polymerization; transmembrane transport; anion transport

Research Articles on VDAC2

1. Study data support a role of VDAC2 as direct effector of ceramide-mediated cell death, providing a molecular framework for how ceramides exert their anti-neoplastic activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VDAC2 antibody

Reference Product	PubMed Publications
BAK1 antibody	>8 publications with VDAC2 and BAK1

Pathways associated with anti-VDAC2 antibody

Products by Pathway	Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Parkinson's Disease Pathway antibodies	Parkinson's Disease Pathway Diagram
CGMP-PKG Signaling Pathway antibodies	CGMP-PKG Signaling Pathway Diagram
CGMP-PKG Signaling Pathway antibodies	CGMP-PKG Signaling Pathway Diagram

Diseases associated with anti-VDAC2 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>11 publications with VDAC2 and Nervous System Diseases
Brain Diseases Antibodies	>7 publications with VDAC2 and Brain Diseases
Infertility, Male Antibodies	>6 publications with VDAC2 and Infertility, Male
Carcinoma Antibodies	>5 publications with VDAC2 and Carcinoma
Necrosis Antibodies	>4 publications with VDAC2 and Necrosis
Cardiovascular Diseases Antibodies	>3 publications with VDAC2 and Cardiovascular Diseases
Liver Neoplasms Antibodies	>3 publications with VDAC2 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>3 publications with VDAC2 and Carcinoma, Hepatocellular
Mental Disorders Antibodies	>3 publications with VDAC2 and Mental Disorders
Liver Diseases Antibodies	>3 publications with VDAC2 and Liver Diseases

Organs/Tissues associated with anti-VDAC2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>16 publications with VDAC2 and Brain
Muscle Antibodies	>8 publications with VDAC2 and Muscle
Heart Antibodies	>8 publications with VDAC2 and Heart
Blood Antibodies	>6 publications with VDAC2 and Blood
Liver Antibodies	>5 publications with VDAC2 and Liver
Nerve Antibodies	>4 publications with VDAC2 and Nerve
Eye Antibodies	>3 publications with VDAC2 and Eye
Vascular Antibodies	>3 publications with VDAC2 and Vascular
Ovary Antibodies	>3 publications with VDAC2 and Ovary
Kidney Antibodies	>3 publications with VDAC2 and Kidney