• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

VDAC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9144875

This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VDAC2, Polyclonal Antibody
Full Product Name
VDAC2 Rabbit pAb
Product Gene Name
anti-VDAC2 antibody
Product Synonym Names
VDAC2; POR
Immunogen Sequence
QNVTAEDTDS IGLALFAPHS SRNYQQHWIL VTCQALGEQV IALSVGNKPS LTNPFPAVEP AVVKFVCAPP SRLTLAPVYT SPQLDMSCPL LQQNKQVVPV SSHRNPRLDL AAYDQEGRRF DNFSSLSIQW ESTRPVLASI EPELPMQLVS QDDESGQKKL HGLQAILVHE ASGTTAITAT ATGYQESHLS SARTKQPHDP L
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
105,810 Da
OMIM
607703
3D Structure
ModBase 3D Structure for Q8TEM1
Positive Samples
Mouse brain, Rat brain
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human VDAC2 (NP_001171712.1).
Cellular Location
Mitochondrion outer membrane

Product Categories/Family for anti-VDAC2 antibody

Cancer; Signal Transduction; Endocrine & Metabolism; Mitochondrial metabolism; Mitochondrial markers; Warburg Effect; Neuroscience; Neurodegenerative Diseases; Polyclonal Antibodies
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-VDAC2 antibody
Western Blot (WB)
Application Notes for anti-VDAC2 antibody
WB: 1:500-1:2000
Customer Validation: WB (Danio rerio)

Western Blot (WB) of anti-VDAC2 antibody

Western blot analysis of extracts of various cell lines, using VDAC2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
Rabbit Anti-VDAC2 Polyclonal Antibody – Cat# MBS9144875

Other Notes

Small volumes of anti-VDAC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VDAC2 purchase

MBS9144875 is an antibody targeting VDAC2. Also known as VDAC2 Rabbit pAb. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VDAC2. It may not necessarily be applicable to this product.

NCBI GI #
27477134
NCBI GeneID
23225
NCBI Accession #
NP_079199.2
UniProt Primary Accession #
Q8TEM1
UniProt Secondary Accession #
O94980; Q6NXG6; Q8NBJ1; Q9H6C8; Q9UFP3; A6NN56
UniProt Related Accession #
Q8TEM1
GenBank Nucleotide #
NM_024923.3
NCBI Official Full Name
nuclear pore membrane glycoprotein 210
NCBI Official Synonym Full Names
nucleoporin 210kDa
NCBI Official Symbol
NUP210
NCBI Official Synonym Symbols
GP210; POM210
UniProt Protein Name
Nuclear pore membrane glycoprotein 210
UniProt Synonym Protein Names
Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDa
Protein Family
Mitochondrial outer membrane protein porin
UniProt Gene Name
NUP210
UniProt Synonym Gene Names
KIAA0906; Nuclear pore protein gp210; POM210
UniProt Entry Name
PO210_HUMAN
NCBI Protein Information
nuclear pore membrane glycoprotein 210; nuclear envelope pore membrane protein POM 210; nuclear pore protein gp210; nucleoporin Nup210; pore membrane protein of 210 kDa

NCBI Summary for VDAC2

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]
Show more

UniProt Comments for VDAC2

NUP210: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Belongs to the NUP210 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; membrane; nuclear envelope; nuclear pore

Molecular Function: protein dimerization activity

Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; protein transport; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; transmembrane transport
Show more

Research Articles on VDAC2

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VDAC2 antibody

 Reference Product  PubMed Publications
 NUP214 antibody  >2 publications with VDAC2 and NUP214
 NUP153 antibody  >2 publications with VDAC2 and NUP153
 NUP107 antibody  >1 publications with VDAC2 and NUP107

Pathways associated with anti-VDAC2 antibody

 Products by Pathway  Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies  Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram

Diseases associated with anti-VDAC2 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >41 publications with VDAC2 and Liver Diseases
 Hepatitis Antibodies  >10 publications with VDAC2 and Hepatitis
 Inflammation Antibodies  >5 publications with VDAC2 and Inflammation
 Disease Models, Animal Antibodies  >4 publications with VDAC2 and Disease Models, Animal
 Carcinoma, Hepatocellular Antibodies  >2 publications with VDAC2 and Carcinoma, Hepatocellular
 Mitochondrial Diseases Antibodies  >2 publications with VDAC2 and Mitochondrial Diseases
 Necrosis Antibodies  >2 publications with VDAC2 and Necrosis
 Breast Neoplasms Antibodies  >1 publications with VDAC2 and Breast Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with VDAC2 and Liver Neoplasms, Experimental
 Fibrosis Antibodies  >1 publications with VDAC2 and Fibrosis

Organs/Tissues associated with anti-VDAC2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >42 publications with VDAC2 and Liver
 Blood Antibodies  >24 publications with VDAC2 and Blood
 Kidney Antibodies  >3 publications with VDAC2 and Kidney
 Embryonic Tissue Antibodies  >3 publications with VDAC2 and Embryonic Tissue
 Connective Tissue Antibodies  >1 publications with VDAC2 and Connective Tissue
 Cervix Antibodies  >1 publications with VDAC2 and Cervix
 Heart Antibodies  >1 publications with VDAC2 and Heart
 Stomach Antibodies  >1 publications with VDAC2 and Stomach
 Spleen Antibodies  >1 publications with VDAC2 and Spleen
 Nerve Antibodies  >1 publications with VDAC2 and Nerve
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000