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VISA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6505833

VISA is an important protein required for innate immune defence against viruses. VISA acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B,… More details

$1180 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VISA, Polyclonal Antibody
Full Product Name
VISA (Virus-Induced Signaling Adapter, Mitochondrial Antiviral Signaling Protein, MAVS, CARD Adapter Inducing Interferon-beta, Cardif, IPS-1) (MaxLight 490)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight490.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human VISA. Reacts with full length VISA isoform 1. Does not react with isoforms 2, 3, 5 or 6, reactivity with isoform 4 is unknown. Species crossreactivity: mouse, rat
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Immunogen
Synthetic peptide corresponding to a 17aa sequence near the center of human VISA.
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-VISA antibody

Applications Tested/Suitable for anti-VISA antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-VISA antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-VISA antibody

Western Blot analysis of rat brain lysate probed with MBS621327 at 0.5ug/ml (A), 1ug/ml(B) and 2ug/ml(C).
Rabbit Anti-VISA Polyclonal Antibody – Cat# MBS6505833

Testing Data of anti-VISA antibody

Immunohistological staining of mouse brainMBS621327.
Rabbit Anti-VISA Polyclonal Antibody, Testing Data – Cat# MBS6505833

Product References and Citations for anti-VISA antibody

1. Seth, R.B., et al. (2006). Antiviral innate immunity pathways. Cell Res. 16:141-7 2. Xu LG, et al. (2005). VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19:727-40. 3. Meylan E, et al. (2005). Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437(7062):1167-72.

Other Notes

Small volumes of anti-VISA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VISA purchase

MBS6505833 is an antibody targeting VISA. Also known as VISA (Virus-Induced Signaling Adapter, Mitochondrial Antiviral Signaling Protein, MAVS, CARD Adapter Inducing Interferon-beta, Cardif, IPS-1) (MaxLight 490). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VISA. It may not necessarily be applicable to this product.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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